Background: A remarkable relationship exists between the upper and lower airways. Bronchial obstruction is a paramount feature of asthma, and its reversibility is considered a main step in asthma diagnosis. Objective: To investigate the degree of bronchodilation and possible risk factors related to it in patients with moderate-severe persistent allergic rhinitis alone. Methods: A total of 375 patients with moderate-severe persistent allergic rhinitis and 115 controls were prospectively and consecutively evaluated by means of clinical examination, skin prick testing, spirometry, and bronchodilation testing. Results: Patients with rhinitis showed a significant increase in forced expiratory volume in 1 second (FEV1) after bronchodilation testing compared with basal values and levels in controls (P <.001). Two-thirds of the rhinitic patients had reversibility (≥12% basal levels). Patients with reversibility had lower FEV1 levels, longer rhinitis duration, and mite and tree allergies. Conclusions: This study highlights the close link between the upper and lower airways and the relevance of performing bronchodilation testing in patients with moderate-severe persistent allergic rhinitis.
|Number of pages||5|
|Journal||Annals of Allergy, Asthma and Immunology|
|Publication status||Published - Jul 2008|
ASJC Scopus subject areas
- Immunology and Allergy