Impact of carotid intima-media thickening on risk stratification in elderly hypertensives

Cesare Cuspidi, Iassen Michev, Giuseppe Macca, Stefano Meani, Maurizio Salerno, Christiana Valerio, Laura Lonati, Gastone Leonetti, Fabio Magrini, Alberto Zanchetti

Research output: Contribution to journalArticlepeer-review


Background: It has been shown that aging and arterial hypertension are both associated with an increased prevalence of carotid structural abnormalities, such as intima-media (IM) thickening or plaques, which are a powerful independent predictor of cardiovascular (CV) events. We investigated the impact of carotid IM thickening in profiling the absolute CV risk stratification according the 1999 World Health Organization/International Society of Hypertension (WHO/ISH) guidelines in elderly hypertensive patients. Methods: Two hundred and thirty untreated elderly patients (>65 years) referred to our outpatient hospital clinic were included in the study. They underwent the following procedures: (i) medical history, physical examination and clinic blood pressure measurement; (ii) routine blood chemistry and urine analysis; (iii) electrocardiogram. The risk was initially stratified according to the routine procedures indicated by WHO/ISH guidelines and subsequently reassessed by adding the results of carotid ultrasonography (IM thickening as diffuse IM thickness >0.9 and

Original languageEnglish
Pages (from-to)25-31
Number of pages7
JournalBlood Pressure
Issue number1
Publication statusPublished - 2003


  • Cardiovascular risk stratification
  • Carotid intima-media thickening
  • Elderly
  • Hypertension
  • Ultrasonography

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine


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