Abstract
In our study we considered the possible interference of cefetamet-pivoxil with the intestinal microflora. We used 60 germ-free mice in which an intestinal microflora similar to the human one had been implanted. They were treated with 14.3 mg/Kg/die (standard dose) and a 28.6 mg/kg/die (daily dose) of cefetamet-pivoxil by oral route. The results obtained in vivo proved that cefetamet-pivoxil at therapeutic doses does not influence the normal intestinal microflora.
Original language | English |
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Pages (from-to) | 246-250 |
Number of pages | 5 |
Journal | Journal of Chemotherapy |
Volume | 6 |
Issue number | 4 |
Publication status | Published - 1994 |
Keywords
- cefetamet-pivoxil
- gnotobiotic mice
- intestinal microflora
ASJC Scopus subject areas
- Microbiology (medical)
- Pharmacology (medical)