Impact of cefetamet-pivoxil on intestinal microflora: In vivo study

M. R. Gismondo, L. Drago, A. Lombardi, C. Fassina

Research output: Contribution to journalArticlepeer-review

Abstract

In our study we considered the possible interference of cefetamet-pivoxil with the intestinal microflora. We used 60 germ-free mice in which an intestinal microflora similar to the human one had been implanted. They were treated with 14.3 mg/Kg/die (standard dose) and a 28.6 mg/kg/die (daily dose) of cefetamet-pivoxil by oral route. The results obtained in vivo proved that cefetamet-pivoxil at therapeutic doses does not influence the normal intestinal microflora.

Original languageEnglish
Pages (from-to)246-250
Number of pages5
JournalJournal of Chemotherapy
Volume6
Issue number4
Publication statusPublished - 1994

Keywords

  • cefetamet-pivoxil
  • gnotobiotic mice
  • intestinal microflora

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology (medical)

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