Impact of COVID-19 on medical treatment patterns in gynecologic oncology: a MITO group survey

MITO group

Research output: Contribution to journalArticlepeer-review


OBJECTIVE: COVID-19 is a global public health emergency. The increasing spread of COVID-19 presents challenges for the clinical care of patients with gynecological tumors. The Multicenter Italian Trials in Ovarian cancer and gynecologic malignancies (MITO) performed a survey to evaluate the impact of the COVID-19 pandemic on medical treatment of gynecological cancer, with a focus on chemotherapy and oral treatment with poly(ADP)-ribose polymerase inhibitors (PARP-i).

METHODS: The survey consisted of a self-administered online questionnaire, sent via email between November 2020 and January 2021 to all members of MITO group.

RESULTS: Forty-nine centers completed the questionnaire. The majority of respondents (83%) use screening tests to determine COVID-19 status in patients who were to undergo chemotherapy or oral medications. All respondents to our survey continued cancer therapy in patients who tested negative for COVID-19 during the pandemic. Seventy-three percent of respondents declared they stopped treatment with chemotherapy or PARP-i only after a positive swab and resumed therapy when negative tests were confirmed.

CONCLUSIONS: COVID-19 positivity impacted patterns of treatment in patients diagnosed with ovarian cancer within the MITO group. Further investigations are needed to evaluate whether these modifications influence oncological clinical outcomes.

Original languageEnglish
Pages (from-to)1363-1368
Number of pages6
JournalInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Issue number10
Publication statusPublished - Oct 2021


  • Administration, Oral
  • Adult
  • Aged
  • Antineoplastic Agents/therapeutic use
  • COVID-19/complications
  • COVID-19 Testing/statistics & numerical data
  • Female
  • Genital Neoplasms, Female/complications
  • Health Care Surveys
  • Health Services Accessibility/statistics & numerical data
  • Humans
  • Italy
  • Male
  • Middle Aged
  • Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use
  • Practice Patterns, Physicians'/statistics & numerical data
  • Withholding Treatment/statistics & numerical data


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