Impact of diabetes on the current in-hospital management of heart failure. From the TEMISTOCLE study

Cristina Opasich, Massimo Cafiero, Marino Scherillo, Stefania De Feo, Francesco Caputo, Lucio Gonzini, Rinaldo Lavecchia, Franco Loru, Aldo P. Maggioni

Research output: Contribution to journalArticlepeer-review


Background. Little is known about the clinical profile, use of resources, management and outcome of a large population of diabetic patients with heart failure managed in a community setting. Methods. A prospective cross-sectional survey in the setting of acute hospital admissions for heart failure to 167 cardiology and 250 internal medicine departments between February 14 and 25, 2000. Results. Among the 2127 consecutively admitted patients, 603 (28.4%) had a history of diabetes; they were significantly younger, had a lower rate of atrial fibrillation, and a more frequent ischemic etiology than non-diabetics. Just as non-diabetic patients, diabetics underwent invasive and non-invasive procedures in a low percentage of cases, even though slightly more frequently when managed by cardiologists. Diabetic patients were less frequently prescribed amiodarone and anticoagulants, and more frequently prescribed nitrates and antiplatelets. The all-cause in-hospital mortality rate was similar among diabetics and non-diabetics (5.3 vs-5.7%, p = NS). Adjusted analysis confirmed that diabetes is not independently associated with a worse outcome. Conclusions. In a community setting diabetes per se has only a slight impact on the management and outcome of patients with heart failure.

Original languageEnglish
Pages (from-to)685-694
Number of pages10
JournalItalian Heart Journal
Issue number10
Publication statusPublished - Oct 2003


  • Diabetes mellitus
  • Heart failure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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