Impact of fasting glycemia and regional cerebral perfusion in diabetic subjects: A study with technetium-99m-ethyl cysteinate dimer single photon emission computed tomography

Francesco Cosentino, Rodolfo Battista, Angelo Scuteri, Francesco De Sensi, Luca De Siati, Carmen Di Russo, Giovanni G. Camici, Massimo Volpe

Research output: Contribution to journalArticle

Abstract

BACKGROUND AND PURPOSE: Diabetes mellitus increases the risk of ischemic stroke. The aim of this study was to investigate the correlation between fasting plasma glucose (FPG) and changes in regional cerebral perfusion (CP) in subjects with DM. METHODS: CP was assessed in 24 subjects (mean age 44±2.5 years) with type 1 diabetes mellitus by single photon emission computed tomography. RESULTS: Analysis of CP during elevated FPG (224±24 mg/dL) showed 3 or more deficits in 42% of the subjects. A positive relationship between the number of CP deficits and FPG was observed (P

Original languageEnglish
Pages (from-to)306-308
Number of pages3
JournalStroke
Volume40
Issue number1
DOIs
Publication statusPublished - Jan 1 2009

Keywords

  • Cerebral blood flow
  • Diabetes mellitus
  • Endothelium
  • SPECT

ASJC Scopus subject areas

  • Medicine(all)
  • Cardiology and Cardiovascular Medicine
  • Clinical Neurology
  • Advanced and Specialised Nursing

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