Impact of machines on plan quality: Volumetric modulated arc therapy and intensity modulated radiation therapy

S. Clemente, M. Cozzolino, C. Oliviero, A. Fiorentino, C. Chiumento, V. Fusco

Research output: Contribution to journalArticlepeer-review


Purpose: To evaluate the impact of different machines on plan quality using both intensity modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) techniques. Materials and methods: Eight patients with squamous cell carcinoma of the oropharynx were selected at random. Plans were computed for IMRT and VMAT Smart Arc, using Pinnacle TPS for an Elekta (IMRT-E, VMAT-E) and Varian linac (IMRT-V, VMAT-V). A three-dose level prescription was used to deliver 70, 63 and 58.1 Gy to regions of macroscopic, microscopic high- and low-risk disease, respectively. All doses were given in 35 fractions. Comparisons were performed on dose-volume histogram data, monitor units (MU), and delivery time. Results: VMAT-E plans resulted slightly MU efficient (-24 % p <0.05) compared to VMAT-V while IMRT-V shortened delivery time (-19 % p <0.05) compared to IMRT-E. All the delivery techniques resulted in equivalent target coverage in terms of D98 % and D2 %. For VMAT technique, a significant improvement of 7 % in homogeneity index (HI) for PTV58.1 was observed for Varian machine. A slight improvement in OARs sparing was observed with Elekta machine both for IMRT and VMAT techniques. Conclusion: Similar plan quality was observed for Elekta and Varian linacs, significant differences were observed in delivery efficiency, as MU number and delivery times, in favor of Elekta and Varian, respectively.

Original languageEnglish
Pages (from-to)141-146
Number of pages6
JournalClinical and Translational Oncology
Issue number2
Publication statusPublished - Feb 2014


  • IMRT
  • Varian and Elekta linacs
  • VMAT

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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