Impact of pericardial effusion on cardiac mechanics in patients with dilated cardiomyopathy

Francesco Scardulla, Antonino Rinaudo, Cesare Scardulla, Salvatore Pasta

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Dilated cardiomyopathy (CDM) is a degenerative disease of the myocardium accompanied by left ventricular (LV) remodeling, resulting in an impaired pump performance. Differently, pericardial effusion (PE) is a liquid accumulation in the pericardial cavity, which may inhibit blood filling of heart chambers. Clinical evidence show that PE may improve pump performance in patients with CDM. Therefore, this study aims to assess wall stress and global function of patients with CDM, PE as compared to healthy patient. These findings suggests that CDM has an important implication in the mechanical changes of LV and right ventricle by increasing wall stress and reducing pump function. Conversely, PE determines lowering myocardial fiber stress and improves global function as compared to those of CDM.

Original languageEnglish
Title of host publicationSIMULTECH 2013 - Proceedings of the 3rd International Conference on Simulation and Modeling Methodologies, Technologies and Applications
Pages639-643
Number of pages5
Publication statusPublished - 2013
Event3rd International Conference on Simulation and Modeling Methodologies, Technologies and Applications, SIMULTECH 2013 - Reykjavik, Iceland
Duration: Jul 29 2013Jul 31 2013

Other

Other3rd International Conference on Simulation and Modeling Methodologies, Technologies and Applications, SIMULTECH 2013
CountryIceland
CityReykjavik
Period7/29/137/31/13

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Keywords

  • Cardiac Mechanics
  • Cardiomyopathy
  • Finite Element Analysis
  • Pericardial Effusion

ASJC Scopus subject areas

  • Information Systems
  • Electrical and Electronic Engineering

Cite this

Scardulla, F., Rinaudo, A., Scardulla, C., & Pasta, S. (2013). Impact of pericardial effusion on cardiac mechanics in patients with dilated cardiomyopathy. In SIMULTECH 2013 - Proceedings of the 3rd International Conference on Simulation and Modeling Methodologies, Technologies and Applications (pp. 639-643)