Impact of preoperative CA 15-3 levels in operable breast cancer. Comparison with tissue polypeptide antigen (TPA) and carcinoembryonic antigen (CEA)

R. V. Iaffaioli, F. Caponigro, G. Esposito, C. Pagliarulo, S. Deplacido, B. Ungaro, L. Bazzicalupo, G. Frasci, A. R. Bianco

Research output: Contribution to journalArticle

Abstract

CA 15-3, TPA and CEA were assayed before surgery in 60 patients with breast cancer. A significant association was found between preoperative CA 15-3 levels and some of the most important prognostic factors in breast cancer, such as lymph node status and tumor size. No similar association was discovered for CEA and TPA. Preoperative CA 15-3 levels were also significantly associated with early recurrences of the disease, thus adding useful information to prognosis especially in N+ patients.

Original languageEnglish
Pages (from-to)21-24
Number of pages4
JournalInternational Journal of Biological Markers
Volume6
Issue number1
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Immunology
  • Biochemistry

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