Impact of surgery for stage IA non-smallcell lung cancer on patient quality of life

Rebecca M. Schwartz, Rowena Yip, Ingram Olkin, Daniel Sikavi, Emanuela Taioli, Claudia Henschke, David F. Yankelevitz, Dongming Xu, Mary Salvatore, Raja Flores, Andrea Wolf, Dorothy I. McCauley, Mildred Chen, Daniel M. Libby, James P. Smith, Mark Pasmantier, Nasser Altorki, A. P. Reeves, Steven Markowitz, Albert MillerJose Cervera Deval, Heidi Roberts, Demetris Patsios, Shusuke Sone, Takaomi Hanaoka, Javier Zulueta, Juan De Torres, Maria D. Lozano, Ralph Aye, Kristin Manning, Tomas Bauer, Stefano Canitano, Salvatore Giunta, Enser Cole, Karl Klingler, John H M Austin, Gregory D N Pearson, Dorith Shaham, Cheryl Aylesworth, Patrick Meyers, Shahriyour Andaz, Davood Vafai, David Naidich, Georgeann McGuinness, Barry Sheppard, Matthew Rifkin, M. Kristin Torsen, Richard Hansen, Samuel Kopel, William Mayfeld, Dan Luedke, Donald Klippenstein, Alan Litwin, Peter A. Loud, Leslie J. Kohman, Ernest M. Scalzetti, Richard Turer, Nestor Villazamar, Arfa Khan, Rakesh Shah, Xueguo Liu, Gary Herzog, Diana Yeh, Ning Wu, Joseph Lowry, Carmine Frumiento, David S. Mendelson, Michael V. Smith, Robert Korst, Jana Taylor, Michelle S. Ginsberg, Michaela Straznicka, Mark Widmann, Gary Cecchi, Terence A S Matalon, Paul Scheinberg, Shari Lynn Odzer, David Olsen, Fred Grannis, Arnold Rotter, Daniel Ray, David Mullen, Peter H. Wiernik, Edson H. Cheung, Melissa Lim, Louis DeCunzo, Robert Glassberg, Harvey Pass, Carmen Endress, Mark Yoder, Palmi Shah, Laura Welch, Michael Kalafer, Jeremy Green, James Walsh, David Bertsch, Elmer Bamacho, Cynthia Chin, James O'Brien, James C. Willey

Research output: Contribution to journalArticle

Abstract

Background There is a paucity of literature comparing quality of life (QoL) before and after surgery in stage IA lung cancer, where surgical resection is the recommended curative treatment. Objective To assess the impact of surgery on physical and mental health-related QoL in patients with stage IA lung cancer treated with surgical resection. Methods Participants in the I-ELCAP cohort who were diagnosed with their frst primary pathologic stage IA non-small-cell lung cancer, underwent surgery, and provided follow-up information on QoL 1 year later were included in the present analysis (N = 107). QoL information was collected using the SF-12 (12-item Short Form Health Survey), which generates 2 component scores related to mental health and physical health. Results Statistical analyses indicated that physical health QoL was signifcantly worsened from before surgery to after surgery, whereas mental health QoL marginally improved from before to after surgery. Physical health QoL worsened for women from baseline to follow-up, but not for men. Only lobectomy (not limited resection) had an impact on QoL from before to after surgery. Limitations Results are considered preliminary given the small sample size and multiple comparisons. Conclusions The current study fndings have implications for lung cancer health care professionals in regard to how they can most effectively present the possible impact of surgery on quality of life to this subset of patients in which disease has not yet signifcantly progressed.

Original languageEnglish
Pages (from-to)37-44
Number of pages8
JournalJournal of Community and Supportive Oncology
Volume14
Issue number1
DOIs
Publication statusPublished - Jan 1 2016

ASJC Scopus subject areas

  • Hematology
  • Oncology

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    Schwartz, R. M., Yip, R., Olkin, I., Sikavi, D., Taioli, E., Henschke, C., Yankelevitz, D. F., Xu, D., Salvatore, M., Flores, R., Wolf, A., McCauley, D. I., Chen, M., Libby, D. M., Smith, J. P., Pasmantier, M., Altorki, N., Reeves, A. P., Markowitz, S., ... Willey, J. C. (2016). Impact of surgery for stage IA non-smallcell lung cancer on patient quality of life. Journal of Community and Supportive Oncology, 14(1), 37-44. https://doi.org/10.12788/jcso.0205