Impact of the first Covid-19 pandemic wave on first episode psychosis in Milan, italy.

C. M. Esposito, A. D'Agostino, B. Dell Osso, A. Fiorentini, C. Prunas, A. Callari, L. Oldani, E. Fontana, G. Gargano, B. Viscardi, B. Giordano, S. D'Angelo, F. Wiedenmann, M. Macellaro, F. Giorgetti, Ne Turtulici, O. Gambini, P. Brambilla

Research output: Contribution to journalArticlepeer-review

Abstract

The ongoing Corona Virus Disease 2019 (COVID–19) pandemic appears to increase risk for mental illness, either directly due to inflammation caused by the virus or indirectly due to related psychosocial stress, resulting in the development of both anxious-depressive and psychotic symptoms. The purpose of the present study was to assess the frequency and characteristics of all patients with First Episodes Psychosis (FEP) without COVID-19 infection hospitalized in the first four months since lockdown in Milan. We recruited sixty-two patients hospitalized between March 8 to July 8, 2020 versus those first hospitalized in the same period in 2019. The two subgroups were compared for sociodemographic variables and clinical characteristics of the episodes. Patients with FEP in 2020 were significantly older than patients with FEP in 2021, and presented with significantly less substances abuse. Interestingly, patients presenting with FEP in 2020 were significantly older than patients with FEP in 2019. These data are compatible with the greater vulnerability to stressful factors during the pandemic, as well as with the greater concern regarding a possible COVID-19 infection producing brain damage causing the FEP.

Original languageEnglish
Article number113802
JournalPsychiatry Research
Volume298
DOIs
Publication statusPublished - Apr 2021

Keywords

  • Brief Psychotic Episode
  • Covid-19
  • First-Episode Psychosis
  • Reactive Psychosis
  • SARS-CoV-2

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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