Impact of type of liver resection on the outcome of colorectal liver metastases: A case-matched analysis

Eleonora Guzzetti, Carlo Pulitanò, Marco Catena, Marcella Arru, Francesca Ratti, Renato Finazzi, Luca Aldrighetti, Gianfranco Ferla

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Wedge resection (WR) for colorectal liver metastases (CLM) has become more common in an attempt to preserve liver parenchyma. However, some investigator have reported that WR is associated with a higher incidence of positive margin and an inferior survival compared with anatomic resection (AR) [1]. Objectives: This study evaluated survival, margin status, and pattern of recurrence of patients with CLM treated with WR or AR. Methods: We identified 208 consecutive patients, in a single institutional database from 1995 to 2004, who underwent either WR or AR. WR was defined as a nonanatomic resection and AR was defined as single resection of one or two liver segments. Patients with combined WR-AR and patients requiring resection of more than two segments or radiofrequency ablation were excluded from the analysis. Results: One hundred six patients underwent WR and 102 patients had AR. There were no differences in the rate of positive surgical margin (P = 0.146), overall recurrence rates (P = 0.211), and patterns of recurrence between the two groups (P = 0.468). The median survival was 32 months for WR and 42 for AR, with 5-year survival rates of 29% and 27% respectively, with no significant difference (P = 0.308). Morbidity was similar between the two groups. Conclusions: WR is a safe procedure and does not disadvantage the patients in terms of tumor recurrence and overall survival.

Original languageEnglish
Pages (from-to)503-507
Number of pages5
JournalJournal of Surgical Oncology
Volume97
Issue number6
DOIs
Publication statusPublished - May 1 2008

Keywords

  • Anatomic resection
  • Colorectal liver metastases
  • Liver surgery
  • Type of liver resection
  • Wedge resection

ASJC Scopus subject areas

  • Surgery
  • Oncology

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