TY - JOUR
T1 - Impaired gait in ankylosing spondylitis
AU - Del Din, Silvia
AU - Carraro, Elena
AU - Sawacha, Zimi
AU - Guiotto, Annamaria
AU - Bonaldo, Lara
AU - Masiero, Stefano
AU - Cobelli, Claudio
PY - 2011/7
Y1 - 2011/7
N2 - Ankylosing spondylitis (AS) is a chronic, inflammatory rheumatic disease. The spine becomes rigid from the occiput to the sacrum, leading to a stooped position. This study aims at evaluating AS subjects gait alterations. Twenty-four subjects were evaluated: 12 normal and 12 pathologic in stabilized anti-TNF-alpha treatment (mean age 49.42 (10.47), 25.44 (3.19) and mean body mass index 55.75 (3.19), 23.73 (2.7), respectively). Physical examination and gait analysis were performed. A motion capture system synchronized with two force plates was used. Three-dimensional kinematics and kinetics of trunk, pelvis, hip, knee and ankle were determined during gait. A trend towards reduction was found in gait velocity and stride length. Gait analysis results showed statistically significant alterations in the sagittal plane at each joint for AS patients (P <0.049). Hip and knee joint extension moments showed a statistically significant reduction (P <0.044). At the ankle joint, a decreased plantarflexion was assessed (P <0.048) together with the absence of the heel rocker. Gait analysis, through gait alterations identification, allowed planning-specific rehabilitation intervention aimed to prevent patients' stiffness together with improve balance and avoid muscles' fatigue.
AB - Ankylosing spondylitis (AS) is a chronic, inflammatory rheumatic disease. The spine becomes rigid from the occiput to the sacrum, leading to a stooped position. This study aims at evaluating AS subjects gait alterations. Twenty-four subjects were evaluated: 12 normal and 12 pathologic in stabilized anti-TNF-alpha treatment (mean age 49.42 (10.47), 25.44 (3.19) and mean body mass index 55.75 (3.19), 23.73 (2.7), respectively). Physical examination and gait analysis were performed. A motion capture system synchronized with two force plates was used. Three-dimensional kinematics and kinetics of trunk, pelvis, hip, knee and ankle were determined during gait. A trend towards reduction was found in gait velocity and stride length. Gait analysis results showed statistically significant alterations in the sagittal plane at each joint for AS patients (P <0.049). Hip and knee joint extension moments showed a statistically significant reduction (P <0.044). At the ankle joint, a decreased plantarflexion was assessed (P <0.048) together with the absence of the heel rocker. Gait analysis, through gait alterations identification, allowed planning-specific rehabilitation intervention aimed to prevent patients' stiffness together with improve balance and avoid muscles' fatigue.
KW - Ankylosing spondylitis
KW - Gait analysis
KW - Kinematics
KW - Kinetics
KW - Three dimensional
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U2 - 10.1007/s11517-010-0731-x
DO - 10.1007/s11517-010-0731-x
M3 - Article
C2 - 21229328
AN - SCOPUS:79959819043
VL - 49
SP - 801
EP - 809
JO - Medical and Biological Engineering and Computing
JF - Medical and Biological Engineering and Computing
SN - 0140-0118
IS - 7
ER -