Impaired glucose metabolism in heroin and methadone users

A. Ceriello, D. Giugliano, N. Passariello, A. Quatraro, P. Dello Russo, R. Torella, F. D'Onofrio

Research output: Contribution to journalArticlepeer-review


Plasma glucose and insulin responses to both oral and intravenous glucose stimulation were evaluated in heroin and methadone addicts, compared to healthy control subjects. Both groups of addicts had an altered response to oral and intravenous glucose load. These phenomena were linked to a reduced insulin response. Moreover, increased fasting insulin levels in both groups of addicts were observed. These data show that both heroin and methadone addiction may alter glucose metabolism, and, furthermore, stress the findings of similarities between opiate addicts and non-insulin dependent diabetics.

Original languageEnglish
Pages (from-to)430-433
Number of pages4
JournalHormone and Metabolic Research
Issue number9
Publication statusPublished - 1987

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology


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