Impaired neural conduction in crossed visual pathways in patients with ocular hypertension

V. Parisi, G. L. Manni, D. Olzi, F. Oddone, G. Coppola, M. G. Bucci

Research output: Contribution to journalArticle


PURPOSE. To evaluate the neural conduction along crossed and uncrossed visual pathways in patients with ocular hypertension (OHT). METHODS. Fifteen patients (mean age 59.1 ± 6.8 years) with OHT (IOP>22 mmHg, Humphrey 24-2 with mean deviation [MD]>-2 dB) were enrolled. They were compared to 15 age-matched controls. In OHT patients and control subjects, visual evoked potentials (VEPs) were recorded using full-field checkerboard patterns (the check subtended 15′ of visual arc; contrast 80%) reversed at 2 Hz. VEP responses were simultaneously recorded in the homolateral visual cortex (HC) and in the contralateral visual cortex (CC), with respect to the stimulated eye. RESULTS. In OHT patients, VEP P100 implicit times observed in HC and CC were both significantly delayed (analysis of variance, p

Original languageEnglish
Pages (from-to)486-494
Number of pages9
JournalEuropean Journal of Ophthalmology
Issue number6
Publication statusPublished - Nov 2004



  • Ocular hypertension
  • Visual evoked potentials
  • Visual field
  • Visual pathways

ASJC Scopus subject areas

  • Ophthalmology

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