Impaired object identification in idiopathic childhood occipital epilepsy

Claudia Brancati, Carmen Barba, Tiziana Metitieri, Federico Melani, Simona Pellacani, Maria Pia Viggiano, Renzo Guerrini

Research output: Contribution to journalArticle

Abstract

Purpose: To investigate whether children with epilepsy primarily affecting the occipital cortex exhibit impairment of visual object identification and to what extent such a hypothesized dysfunction is related to an interfering functional, rather than structural, process. Method: We studied nine children with idiopathic childhood occipital epilepsy (ICOE) and compared them to eight children with lesional posterior cortex epilepsy (PCEs) and to 60 age-matched controls. We applied an "ascendent" paradigm of object identification, using a coarse-to-fine order procedure, which gradually integrated spatial frequency information from the most blurred image to the complete figure. In children with ICOE, we explored how epilepsy-related variables might be related to object identification task. Key Findings: Children with ICOE and those with PCEs needed more physical information than controls to identify visual stimuli. There was a decreasing accuracy from controls to children with ICOE and from children with ICOE to those with PCEs. Children with ICOE demonstrated slight selective impairment in visuospatial processing and those among them having experienced a higher number of seizures or in whom interictal electroencephalography (EEG) discharges had been present for a longer time, required a higher level of physical information to recognize objects. Significance: The observation that children with ICOE performed worse than controls in object identification, although better than children with PCEs, might indicate that functional disruption caused by epileptiform EEG abnormalities and seizures, can interfere per se with perceptual processes, even in the absence of a lesion. This effect appears to be detected only by perceptual and cognitive screening.

Original languageEnglish
Pages (from-to)686-694
Number of pages9
JournalEpilepsia
Volume53
Issue number4
DOIs
Publication statusPublished - Apr 2012

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Epilepsy
Electroencephalography
Seizures
Occipital Lobe
Vision Disorders

Keywords

  • Childhood occipital epilepsy
  • EEG abnormalities
  • Object identification
  • Visual pathways

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Brancati, C., Barba, C., Metitieri, T., Melani, F., Pellacani, S., Viggiano, M. P., & Guerrini, R. (2012). Impaired object identification in idiopathic childhood occipital epilepsy. Epilepsia, 53(4), 686-694. https://doi.org/10.1111/j.1528-1167.2012.03410.x

Impaired object identification in idiopathic childhood occipital epilepsy. / Brancati, Claudia; Barba, Carmen; Metitieri, Tiziana; Melani, Federico; Pellacani, Simona; Viggiano, Maria Pia; Guerrini, Renzo.

In: Epilepsia, Vol. 53, No. 4, 04.2012, p. 686-694.

Research output: Contribution to journalArticle

Brancati, C, Barba, C, Metitieri, T, Melani, F, Pellacani, S, Viggiano, MP & Guerrini, R 2012, 'Impaired object identification in idiopathic childhood occipital epilepsy', Epilepsia, vol. 53, no. 4, pp. 686-694. https://doi.org/10.1111/j.1528-1167.2012.03410.x
Brancati C, Barba C, Metitieri T, Melani F, Pellacani S, Viggiano MP et al. Impaired object identification in idiopathic childhood occipital epilepsy. Epilepsia. 2012 Apr;53(4):686-694. https://doi.org/10.1111/j.1528-1167.2012.03410.x
Brancati, Claudia ; Barba, Carmen ; Metitieri, Tiziana ; Melani, Federico ; Pellacani, Simona ; Viggiano, Maria Pia ; Guerrini, Renzo. / Impaired object identification in idiopathic childhood occipital epilepsy. In: Epilepsia. 2012 ; Vol. 53, No. 4. pp. 686-694.
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