Impaired short-term motor learning in multiple sclerosis: Evidence from virtual reality

Letizia Leocani, Eleonora Comi, Pietro Annovazzi, Marco Rovaris, Paolo Rossi, Marco Cursi, Mauro Comola, Vittorio Martinelli, Giancarlo Comi

Research output: Contribution to journalArticlepeer-review


Objective. Virtual reality (VR) has been proposed as a potentially useful tool for motor assessment and rehabilitation. The objective of this study was to investigate the usefulness of VR in the assessment of short-term motor learning in multiple sclerosis (MS). Methods. Twelve right-handed MS patients and 12 control individuals performed a motor-tracking task with their right upper limb, following the trajectory of an object projected on a screen along with online visual feedback on hand position from a sensor on the index finger. A pretraining test (3 trials), a training phase (12 trials), and a posttraining test (3 trials) were administered. Distances between performed and required trajectory were computed. Results. Both groups performed worse in depth planes compared to the frontal (x,z) plane (P

Original languageEnglish
Pages (from-to)273-278
Number of pages6
JournalNeurorehabilitation and Neural Repair
Issue number3
Publication statusPublished - Sep 2007


  • Motor learning
  • Multiple sclerosis
  • Upper limb
  • Virtual reality.

ASJC Scopus subject areas

  • Rehabilitation
  • Clinical Neurology
  • Neuroscience(all)
  • Health Professions(all)


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