Impaired splenic function and tuftsin deficiency in patients with intestinal failure on long term intravenous nutrition

G. Zoli, G. R. Corazza, S. Wood, R. Bartoli, G. Gasbarrini, M. J G Farthing

Research output: Contribution to journalArticlepeer-review

Abstract

Background - Reticuloendothelial system function is impaired in humans receiving lipid regimens. Aims - To evaluate the effects of long term administration of long chain triglyceride emulsions on reticuloendothelial system function. Methods - Splenic function and tuftsin activity were measured in 20 patients on intravenous nutrition for intestinal failure, 20 patients with Crohn's disease who were not receiving intravenous nutrition, and 50 healthy controls. Results - Pitted red cells counts in patients on intravenous nutrition (8.0%) were significantly higher (p

Original languageEnglish
Pages (from-to)759-762
Number of pages4
JournalGut
Volume43
Issue number6
Publication statusPublished - 1998

Keywords

  • Home parenteral nutrition
  • Hyposplenism
  • Short bowel syndrome
  • Splenic function
  • Tuftsin

ASJC Scopus subject areas

  • Gastroenterology

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