Impaired uterine artery flow associated with the presence of ovarian endometrioma: Preliminary results of a prospective study

Maria Grazia Porpora, Federica Tomao, Lucia Manganaro, Deliar Yazdanian, Eliana Fuggetta, Maria Grazia Piccioni, Pierluigi Benedetti Panici, Giuseppe Benagiano

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Abstract

Background: Aim of this prospective, case-control study was to evaluate uterine arteries' blood flow before and after laparoscopic surgery in patients with ovarian endometriosis and its possible correlation with infertility. Methods. We prospectively enrolled 110 women of reproductive age; 69 with ovarian endometriomas and scheduled for surgery, and 41 controls. At enrolment, a detailed medical, gynecologic and obstetric history was collected. Fertility and pregnancy desire were assessed. All patients underwent complete physical and gynecologic examination. Transvaginal ultrasound with Doppler color flow was performed to evaluate Resistance Index (RI) of uterine arteries during the secretory phase, at enrolment (T0) and 3 months after laparoscopic surgery (T1). Results: Among cases, 27 patients were excluded because they did not meet the inclusion criteria. At enrolment (T0) unilateral or bilateral flow alterations (RI ≥ 0.8) were found in 38 out of 42 patients with ovarian endometriosis (90%), whereas in the control group only 17 women (41%) had Doppler alterations. The difference in uterine artery RI values between cases and controls was statistically significant (P <0.0001). A statistically significant improvement in uterine artery flow (P

Original languageEnglish
Article number1
JournalJournal of Ovarian Research
Volume7
Issue number1
DOIs
Publication statusPublished - Jan 8 2014

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Keywords

  • Color doppler
  • Endometriosis
  • Infertility
  • Resistance Index (RI)
  • Ultrasounds
  • Uterine artery flow

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynaecology
  • Medicine(all)

Cite this

Porpora, M. G., Tomao, F., Manganaro, L., Yazdanian, D., Fuggetta, E., Piccioni, M. G., Benedetti Panici, P., & Benagiano, G. (2014). Impaired uterine artery flow associated with the presence of ovarian endometrioma: Preliminary results of a prospective study. Journal of Ovarian Research, 7(1), [1]. https://doi.org/10.1186/1757-2215-7-1