Impairment in dating and retrieving remote events in patients with early Parkinson's disease

Annalena Venneri, Paolo Nichelli, Giacomo Modonesi, Maria Angela Molinari, Riccardo Russo, Carla Sardini

Research output: Contribution to journalArticle

Abstract

Remote memory has been studied in a group of 25 non-demented patients with Parkinson's disease and their performance has been compared with that of 22 healthy control subjects. Only patients who scored ≤ 27 on the mini mental state examination and with no anticholinergic treatment were included in the sample. A remote memory questionnaire was given, to evaluate memory for public events that occurred from 1966 to 1990. Each event was probed with five questions concerning its content and one for the date. Compared with healthy subjects, patients with Parkinson's disease were significantly impaired both in recalling the content and in dating remote events. These results support the claim that remote memory in patients with Parkinson's disease is disrupted independently of dementia. This impairment might result from a dysfunction at the level of the circuit connecting the basal ganglia to the frontal lobes.

Original languageEnglish
Pages (from-to)410-413
Number of pages4
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume62
Issue number4
Publication statusPublished - Apr 1997

Keywords

  • Frontal lobe
  • Parkinson's disease
  • Remote memory

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)
  • Psychiatry and Mental health

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    Venneri, A., Nichelli, P., Modonesi, G., Molinari, M. A., Russo, R., & Sardini, C. (1997). Impairment in dating and retrieving remote events in patients with early Parkinson's disease. Journal of Neurology, Neurosurgery and Psychiatry, 62(4), 410-413.