Implantable cardioverter defibrillator prevents sudden cardiac death in systemic sclerosis

Pasquale Bernardo, Maria Letizia Conforti, Silvia Bellando-Randone, Paolo Pieragnoli, Jelena Blagojevic, Olga Kaloudi, Serena Guiducci, Francesco Porta, Luigi Padeletti, Gian Franco Gensini, Marco Matucci-Cerinic

Research output: Contribution to journalArticlepeer-review


Objective. Cardiac involvement means a poor prognosis in systemic sclerosis (SSc). Conduction defects and arrhythmias are frequent in patients with SSc, and may result in sudden cardiac death. We tested whether electrophysiologic studies and implantation of cardioverter defibrillators are recommended when ventricular arrhythmias are present. Method. A cardioverter defibrillator was implanted in 10 patients with SSc who had heart involvement. Result. After 36 months, analysis of the device showed several episodes of ventricular tachycardia in 3 patients, which were promptly reverted by electrical shock delivery. Conclusion. In patients with SSc who are affected by ventricular arrhythmias, the implantation of a cardioverter defibrillator may prevent sudden cardiac death. The Journal of Rheumatology

Original languageEnglish
Pages (from-to)1617-1621
Number of pages5
JournalJournal of Rheumatology
Issue number8
Publication statusPublished - Aug 2011


  • Implantable cardioverter defibrillator
  • Sudden cardiac death
  • Systemic sclerosis
  • Ventricular tachyarrhythmias

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy


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