Implantable devices for constant rate intraperitoneal insulin administration: 1 year follow-up

Intraperitoneal (IP) insulin treatment has been proposed as an alternative approach to conventional subcutaneous (SC) insulin therapy. The rationale for doing that is in the partial portal insulin absorption producing more physiologic plasma insulin kinetics. Both external and implantable devices have been used for IP insulin administration. This study analyzed the clinical feasibility and therapeutic efficacy of a chronic IP insulin treatment by means of an implantable constant rate insulin infusion pump.