Implementation of a consensus set of hypervariable mycobacterial interspersed Repetitive-Unit-Variable-Number Tandem-Repeat loci in Mycobacterium tuberculosis molecular epidemiology

Alberto Gaetano Trovato, Silva Tafaj, Simone Battaglia, Riccardo Alagna, Donika Bardhi, Perlat Kapisyzi, Silvana Bala, Migena Haldeda, Emanuele Borroni, Hasan Hafizi, Daniela Maria Cirillo

Research output: Contribution to journalArticlepeer-review

Abstract

This study shows that the addition of a consensus 4-locus set of hypervariable mycobacterial interspersed repetitive-unit- variable-number tandem repeat (MIRU-VNTR) loci to the spoligotyping-24-locus MIRU-VNTR typing strategy is a wellstandardized approach that can contribute to an improvement of the true cluster definition while retaining high typeability in non-Beijing strains.

Original languageEnglish
Pages (from-to)478-482
Number of pages5
JournalJournal of Clinical Microbiology
Volume54
Issue number2
DOIs
Publication statusPublished - Feb 1 2016

ASJC Scopus subject areas

  • Microbiology (medical)

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