L’implementazione del DNA-HPV come test primario nei programmi italiani di screening del cervicocarcinoma. Risultati del Progetto MIDDIR

Translated title of the contribution: Implementation of DNA-HPV primary screening in Italian cervical cancer screening programmes. Results of the MIDDIR Project

Francesca Di Stefano, Paolo Giorgi Rossi, Francesca Carozzi, Guglielmo Ronco, Laura Cacciani, Simona Vecchi, Carlo Naldoni, Nereo Segnan, Gruppo di lavoro MIDDIR – HPV test in primary screening, Luigina Bonelli

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVES: to obtain data on conversion paths to HPV testing as part of screening programmes and to harmonize the introduction of HPV testing in primary cervical cancer screening protocols of Italian programmes.

DESIGN: survey by questionnaire on strategies adopted by screening programmes for transition to primary HPV testing; systematic review of the literature; discussion among experts. SETTING AND PARTICIPANT S: managers of Italian Regions' cervical cancer screening programmes.

MAIN OUTCOME MEASURES: transition planning; activity volumes; modalities of centralization; criteria for dismissal; staff training; communication initiatives.

RESULTS: nine cervical screening programmes responded to the survey. Most of them chose to schedule a transition of a few years to allow for adjustment of the volume of activity in the passage from the three-year screening interval to the five-year one. To select women to be given precedence, 7 programmes use the age, starting from the oldest. The liquid base is the choice by far preferred both for HPV test and for Pap test. The reading of HPV test "born" already centralized, but a centralization process is in place also for cytology.

CONCLUSIONS: the survey on conversion strategies to primary HPV testing showed the opportunity to schedule a transition phase. For HPV test, cost, organization, and quality benefits of centralization are clear, thus the central organization should be preferred and managed immediately. Moreover, the need for a centralization of cytology is evident. The tariff scheme should be based on the whole process rather than on single performances. Dismissal strategies have to be tailored on peculiarities of single services, but some typologies can be outlined.

Translated title of the contributionImplementation of DNA-HPV primary screening in Italian cervical cancer screening programmes. Results of the MIDDIR Project
Original languageItalian
Pages (from-to)116-124
Number of pages9
JournalEpidemiologia e prevenzione
Volume41
Issue number2
DOIs
Publication statusPublished - Jun 20 2017

Keywords

  • English Abstract
  • Journal Article

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