Implementation of laparoscopic approach for type B radical hysterectomy

A comparison with open surgical operations

Antonino Ditto, Fabio Martinelli, Giorgio Bogani, Maria L. Gasparri, Violante Di Donato, Flavia Zanaboni, Domenica Lorusso, Francesco Raspagliesi

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Objective: To investigate the safety, feasibility and effectiveness of laparoscopic approach in the management patients undergoing modified radical hysterectomy for early stage cervical cancer. Methods: Consecutive data of 157 women who had class II radical hysterectomy, for stage IA2 and stage IB1 0.05). Patients undergoing surgery via laparoscopy experienced longer operative time than patients undergoing RAH; while LRH correlated whit shorter length of hospitalization and lower blood loss in comparison to RAH. Intra- And post-operative complication rate was similar between groups ( p 1/4 1.00). The execution of LRH or RAH did not influence site of recurrence ( p > 0.2) as well as survival outcomes, in term of 5-year disease-free ( p 1/4 0.29, log-rank test) and overall survivals ( p 1/4 0.50, log-rank test). Conclusion: Laparoscopic approach is a safe procedure, upholds the results of RAH, reducing invasiveness of open surgical operations. Further large prospective investigations are warranted.

Original languageEnglish
Pages (from-to)34-39
Number of pages6
JournalEuropean Journal of Surgical Oncology
Volume41
Issue number1
DOIs
Publication statusPublished - 2015

Fingerprint

Hysterectomy
Survival
Operative Time
Uterine Cervical Neoplasms
Laparoscopy
Hospitalization
Safety
Recurrence

Keywords

  • Laparoscopy
  • Morbidity
  • Open surgery
  • Survival
  • Type II radical hysterectomy

ASJC Scopus subject areas

  • Oncology
  • Surgery

Cite this

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title = "Implementation of laparoscopic approach for type B radical hysterectomy: A comparison with open surgical operations",
abstract = "Objective: To investigate the safety, feasibility and effectiveness of laparoscopic approach in the management patients undergoing modified radical hysterectomy for early stage cervical cancer. Methods: Consecutive data of 157 women who had class II radical hysterectomy, for stage IA2 and stage IB1 0.05). Patients undergoing surgery via laparoscopy experienced longer operative time than patients undergoing RAH; while LRH correlated whit shorter length of hospitalization and lower blood loss in comparison to RAH. Intra- And post-operative complication rate was similar between groups ( p 1/4 1.00). The execution of LRH or RAH did not influence site of recurrence ( p > 0.2) as well as survival outcomes, in term of 5-year disease-free ( p 1/4 0.29, log-rank test) and overall survivals ( p 1/4 0.50, log-rank test). Conclusion: Laparoscopic approach is a safe procedure, upholds the results of RAH, reducing invasiveness of open surgical operations. Further large prospective investigations are warranted.",
keywords = "Laparoscopy, Morbidity, Open surgery, Survival, Type II radical hysterectomy",
author = "Antonino Ditto and Fabio Martinelli and Giorgio Bogani and Gasparri, {Maria L.} and {Di Donato}, Violante and Flavia Zanaboni and Domenica Lorusso and Francesco Raspagliesi",
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T1 - Implementation of laparoscopic approach for type B radical hysterectomy

T2 - A comparison with open surgical operations

AU - Ditto, Antonino

AU - Martinelli, Fabio

AU - Bogani, Giorgio

AU - Gasparri, Maria L.

AU - Di Donato, Violante

AU - Zanaboni, Flavia

AU - Lorusso, Domenica

AU - Raspagliesi, Francesco

PY - 2015

Y1 - 2015

N2 - Objective: To investigate the safety, feasibility and effectiveness of laparoscopic approach in the management patients undergoing modified radical hysterectomy for early stage cervical cancer. Methods: Consecutive data of 157 women who had class II radical hysterectomy, for stage IA2 and stage IB1 0.05). Patients undergoing surgery via laparoscopy experienced longer operative time than patients undergoing RAH; while LRH correlated whit shorter length of hospitalization and lower blood loss in comparison to RAH. Intra- And post-operative complication rate was similar between groups ( p 1/4 1.00). The execution of LRH or RAH did not influence site of recurrence ( p > 0.2) as well as survival outcomes, in term of 5-year disease-free ( p 1/4 0.29, log-rank test) and overall survivals ( p 1/4 0.50, log-rank test). Conclusion: Laparoscopic approach is a safe procedure, upholds the results of RAH, reducing invasiveness of open surgical operations. Further large prospective investigations are warranted.

AB - Objective: To investigate the safety, feasibility and effectiveness of laparoscopic approach in the management patients undergoing modified radical hysterectomy for early stage cervical cancer. Methods: Consecutive data of 157 women who had class II radical hysterectomy, for stage IA2 and stage IB1 0.05). Patients undergoing surgery via laparoscopy experienced longer operative time than patients undergoing RAH; while LRH correlated whit shorter length of hospitalization and lower blood loss in comparison to RAH. Intra- And post-operative complication rate was similar between groups ( p 1/4 1.00). The execution of LRH or RAH did not influence site of recurrence ( p > 0.2) as well as survival outcomes, in term of 5-year disease-free ( p 1/4 0.29, log-rank test) and overall survivals ( p 1/4 0.50, log-rank test). Conclusion: Laparoscopic approach is a safe procedure, upholds the results of RAH, reducing invasiveness of open surgical operations. Further large prospective investigations are warranted.

KW - Laparoscopy

KW - Morbidity

KW - Open surgery

KW - Survival

KW - Type II radical hysterectomy

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