Chlamydia pneumoniae has been recently recognized as a common respiratory tract infectious agent. Chronic C. pneumoniae infection has been found to be common in chronic bronchitis and could contribute to disease progression through its toxic effect on bronchial epithelial cells, with ciliostasis and increasing chronic inflammation through proinflammatory cytokine production. C. pneumoniae seems to be significantly related to wheezing in children, particularly in patients with a history of recurrent episodes, and to adult-onset nonatopic asthma. Specific antibiotic therapy may improve the course of reactive airway disease.
|Number of pages||4|
|Journal||Clinical Pulmonary Medicine|
|Publication status||Published - Sep 2002|
- Chlamydia pneumoniae
- Chronic obstructive pulmonary disease
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine