Implications of Chlamydia Pneumoniae in the etiopathogenesis of chronic pulmonary diseases

R. Cosentini, Francesco Blasi, P. Tarsia, S. Centanni, L. Allegra

Research output: Contribution to journalArticle

Abstract

Chlamydia pneumoniae has been recently recognized as a common respiratory tract infectious agent. Chronic C. pneumoniae infection has been found to be common in chronic bronchitis and could contribute to disease progression through its toxic effect on bronchial epithelial cells, with ciliostasis and increasing chronic inflammation through proinflammatory cytokine production. C. pneumoniae seems to be significantly related to wheezing in children, particularly in patients with a history of recurrent episodes, and to adult-onset nonatopic asthma. Specific antibiotic therapy may improve the course of reactive airway disease.

Original languageEnglish
Pages (from-to)249-252
Number of pages4
JournalClinical Pulmonary Medicine
Volume9
Issue number5
Publication statusPublished - Sep 2002

Keywords

  • Asthma
  • Chlamydia pneumoniae
  • Chronic obstructive pulmonary disease

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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