Implicit learning deficit in children with Duchenne muscular dystrophy: Evidence for a cerebellar cognitive impairment?

Research output: Contribution to journalArticle

Abstract

This study aimed at comparing implicit sequence learning in individuals affected by Duchenne Muscular Dystrophy without intellectual disability and age-matched typically developing children. A modified version of the Serial Reaction Time task was administered to 32 Duchenne children and 37 controls of comparable chronological age. The Duchenne group showed a reduced rate of implicit learning even if in the absence of global intellectual disability. This finding provides further evidence of the involvement of specific aspects of cognitive function in Duchenne muscular dystrophy and on its possible neurobiological substrate.

Original languageEnglish
Pages (from-to)e0191164
Number of pages10
JournalPLoS One
Volume13
Issue number1
DOIs
Publication statusPublished - Jan 16 2018

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Keywords

  • Case-Control Studies
  • Cerebellum/physiopathology
  • Child
  • Cognitive Dysfunction/complications
  • Humans
  • Learning/physiology
  • Learning Disorders/complications
  • Logistic Models
  • Male
  • Muscular Dystrophy, Duchenne/complications
  • Reaction Time/physiology

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