Importance of spinal deformity index in risk evaluation of VCF (vertebral compression fractures) in obese subjects: Prospective study

Carlo Ruosi, S. Liccardo, D. Rossi, G. Colella, C. Di Somma, A. Colao

Research output: Contribution to journalArticle

Abstract

Introduction Obesity and osteoporosis share many features and recent studies have identified many similarities suggesting common pathophysiological mechanisms. Obesity is associated with a higher risk of non-traumatic fractures despite bone mineral density (BMD) being normal or even increased. Materials and methods 54 obese subjects were analyzed (51±16 years, 10 males, 44 females). Spinal deformity index (SDI) is a semi-quantitative method that may be a surrogate index of bone microarchitecture. SDI index was higher in patients than in controls. In 87.5 % of patients and 10 % of controlswe found morphometric vertebral fractures, despite a DEXA Tscore not diagnostic of osteoporosis. Conclusion The objective of this study was to assess in obese patients levels of 25OH vitamin D, parathyroid hormone, serum and urinary calcium (Ca) and phosphorus (P), BMD, and SDI. 87.5 % of the obese subjects present nontraumatic vertebral fractures and reduced bone quality as measured by SDI.

Original languageEnglish
JournalEuropean Spine Journal
Volume22
Issue numberSUPPL.6
DOIs
Publication statusPublished - Nov 2013

Keywords

  • Obesity
  • Osteoporosis
  • Spinal deformity index
  • Vertebral fractures

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine
  • Medicine(all)

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