TY - JOUR
T1 - Impressive pseudotumoral proliferative nodules in a giant congenital nevus of a newborn
AU - Palmieri, Giancarlo
AU - Valassina, Maria Francesca Bianciardi
AU - Proia, Giorgio
AU - El Hachem, May
AU - Callea, Francesco
AU - Zama, Mario
PY - 2013/5
Y1 - 2013/5
N2 - The potential for malignant transformation of a giant congenital melanocytic nevus (GCMN), although rare, should be considered, especially in proliferative lesions that have nodules on their surface, as they can clinically and histologically mimic melanoma and generally have a poor prognosis. We present the case of a newborn boy with a giant nevus of uneven blackish color on the back with variable degrees of intensity of pigmentation, almost entirely covered by nodules of large and variable sizes, soft texture, and a tendency to ulcerate and bleed. The unusual clinical and histologic appearance made the case particularly interesting and featured a not well-defined biologic behavior, thus deserving a radical surgical approach to fulfill diagnostic and therapeutic aims.
AB - The potential for malignant transformation of a giant congenital melanocytic nevus (GCMN), although rare, should be considered, especially in proliferative lesions that have nodules on their surface, as they can clinically and histologically mimic melanoma and generally have a poor prognosis. We present the case of a newborn boy with a giant nevus of uneven blackish color on the back with variable degrees of intensity of pigmentation, almost entirely covered by nodules of large and variable sizes, soft texture, and a tendency to ulcerate and bleed. The unusual clinical and histologic appearance made the case particularly interesting and featured a not well-defined biologic behavior, thus deserving a radical surgical approach to fulfill diagnostic and therapeutic aims.
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U2 - 10.1111/j.1525-1470.2012.01845.x
DO - 10.1111/j.1525-1470.2012.01845.x
M3 - Article
C2 - 22958141
AN - SCOPUS:84876896336
VL - 30
JO - Pediatric Dermatology
JF - Pediatric Dermatology
SN - 0736-8046
IS - 3
ER -