Improved control of cisplatin-induced emesis with a metoclopramide-dexamethasone combination

Francesco Cognetti; Paola Pinnaro; Paolo Carlini; Claudio Caporali; Enzo M. Ruggeri; Camillo F. Pollera

doi:10.1007/BF00269037

Improved control of cisplatin-induced emesis with a metoclopramide-dexamethasone combination

Francesco Cognetti, Paola Pinnaro, Paolo Carlini, Claudio Caporali, Enzo M. Ruggeri, Camillo F. Pollera

Istituto Regina Elena

Research output: Contribution to journal › Article › peer-review

Abstract

Twenty-four patients receiving combination chemotherapy including cisplatin at a dosage of 50 mg/m² were entered on this antiemetic randomized open cross-over study. High-dose dexamethasone (DXM) (regimen A) was compared with the combination of DXM and high doses of metoclopramide (MCP) (regimen B). Five patients (20%) treated with regimen A and 13 (54%) treated with regimen B suffered neither hausea nor vomiting (P

Original language	English
Pages (from-to)	235-237
Number of pages	3
Journal	Cancer Chemotherapy and Pharmacology
Volume	13
Issue number	3
DOIs	https://doi.org/10.1007/BF00269037
Publication status	Published - Oct 1984

ASJC Scopus subject areas

Pharmacology
Oncology
Cancer Research

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AU - Cognetti, Francesco

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AU - Carlini, Paolo

AU - Caporali, Claudio

AU - Ruggeri, Enzo M.

AU - Pollera, Camillo F.

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