Improved control of cisplatin-induced emesis with a metoclopramide-dexamethasone combination

Francesco Cognetti, Paola Pinnaro, Paolo Carlini, Claudio Caporali, Enzo M. Ruggeri, Camillo F. Pollera

Research output: Contribution to journalArticlepeer-review

Abstract

Twenty-four patients receiving combination chemotherapy including cisplatin at a dosage of 50 mg/m2 were entered on this antiemetic randomized open cross-over study. High-dose dexamethasone (DXM) (regimen A) was compared with the combination of DXM and high doses of metoclopramide (MCP) (regimen B). Five patients (20%) treated with regimen A and 13 (54%) treated with regimen B suffered neither hausea nor vomiting (P

Original languageEnglish
Pages (from-to)235-237
Number of pages3
JournalCancer Chemotherapy and Pharmacology
Volume13
Issue number3
DOIs
Publication statusPublished - Oct 1984

ASJC Scopus subject areas

  • Pharmacology
  • Oncology
  • Cancer Research

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