Improved Outcome of Alternative Donor Transplantations in Patients with Myelofibrosis: From Unrelated to Haploidentical Family Donors

Stefania Bregante, Alida Dominietto, Anna Ghiso, Anna Maria Raiola, Francesca Gualandi, Riccardo Varaldo, Carmela Di Grazia, Teresa Lamparelli, Silvia Luchetti, Simona Geroldi, Lucia Casarino, Sarah Pozzi, Elisabetta Tedone, Maria Teresa Van Lint, Federica Galaverna, Giovanni Barosi, A. Bacigalupo

Research output: Contribution to journalArticlepeer-review

Abstract

This is a retrospective analysis of 95 patients with myelofibrosis who were allografted between 2001 and 2014. The aims of the study were to assess whether the outcome of alternative donor grafts has improved with time and how this compares with the outcome of identical sibling grafts. Patients were studied in 2 time intervals: 2000 to 2010 (n = 58) and 2011 to 2014 (n = 37). The Dynamic International Prognostic Scoring System score was comparable in the 2 time periods, but differences in the most recent group included older age (58 versus 53 years, P =004), more family haploidentical donors (54% versus 5%, P

Original languageEnglish
Pages (from-to)324-329
Number of pages6
JournalBiology of Blood and Marrow Transplantation
Volume22
Issue number2
DOIs
Publication statusPublished - Feb 1 2016

Keywords

  • Haploidentical donors
  • Myelofibrosis
  • Unrelated donors

ASJC Scopus subject areas

  • Transplantation
  • Hematology

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