Improved Outcome of Alternative Donor Transplantations in Patients with Myelofibrosis: From Unrelated to Haploidentical Family Donors

Stefania Bregante; Alida Dominietto; Anna Ghiso; Anna Maria Raiola; Francesca Gualandi; Riccardo Varaldo; Carmela Di Grazia; Teresa Lamparelli; Silvia Luchetti; Simona Geroldi; Lucia Casarino; Sarah Pozzi; Elisabetta Tedone; Maria Teresa Van Lint; Federica Galaverna; Giovanni Barosi; A. Bacigalupo

doi:10.1016/j.bbmt.2015.09.028

Improved Outcome of Alternative Donor Transplantations in Patients with Myelofibrosis: From Unrelated to Haploidentical Family Donors

Stefania Bregante, Alida Dominietto, Anna Ghiso, Anna Maria Raiola, Francesca Gualandi, Riccardo Varaldo, Carmela Di Grazia, Teresa Lamparelli, Silvia Luchetti, Simona Geroldi, Lucia Casarino, Sarah Pozzi, Elisabetta Tedone, Maria Teresa Van Lint, Federica Galaverna, Giovanni Barosi, A. Bacigalupo

Research output: Contribution to journal › Article › peer-review

Abstract

This is a retrospective analysis of 95 patients with myelofibrosis who were allografted between 2001 and 2014. The aims of the study were to assess whether the outcome of alternative donor grafts has improved with time and how this compares with the outcome of identical sibling grafts. Patients were studied in 2 time intervals: 2000 to 2010 (n = 58) and 2011 to 2014 (n = 37). The Dynamic International Prognostic Scoring System score was comparable in the 2 time periods, but differences in the most recent group included older age (58 versus 53 years, P =004), more family haploidentical donors (54% versus 5%, P

Original language	English
Pages (from-to)	324-329
Number of pages	6
Journal	Biology of Blood and Marrow Transplantation
Volume	22
Issue number	2
DOIs	https://doi.org/10.1016/j.bbmt.2015.09.028
Publication status	Published - Feb 1 2016

Keywords

Haploidentical donors
Myelofibrosis
Unrelated donors

ASJC Scopus subject areas

Transplantation
Hematology

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10.1016/j.bbmt.2015.09.028

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Bregante, S., Dominietto, A., Ghiso, A., Raiola, A. M., Gualandi, F., Varaldo, R., Di Grazia, C., Lamparelli, T., Luchetti, S., Geroldi, S., Casarino, L., Pozzi, S., Tedone, E., Van Lint, M. T., Galaverna, F., Barosi, G., & Bacigalupo, A. (2016). Improved Outcome of Alternative Donor Transplantations in Patients with Myelofibrosis: From Unrelated to Haploidentical Family Donors. Biology of Blood and Marrow Transplantation, 22(2), 324-329. https://doi.org/10.1016/j.bbmt.2015.09.028

Bregante, S , Dominietto, A, Ghiso, A, Raiola, AM , Gualandi, F , Varaldo, R , Di Grazia, C , Lamparelli, T, Luchetti, S, Geroldi, S, Casarino, L, Pozzi, S, Tedone, E, Van Lint, MT, Galaverna, F, Barosi, G & Bacigalupo, A 2016, 'Improved Outcome of Alternative Donor Transplantations in Patients with Myelofibrosis: From Unrelated to Haploidentical Family Donors', Biology of Blood and Marrow Transplantation, vol. 22, no. 2, pp. 324-329. https://doi.org/10.1016/j.bbmt.2015.09.028

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title = "Improved Outcome of Alternative Donor Transplantations in Patients with Myelofibrosis: From Unrelated to Haploidentical Family Donors",

abstract = "This is a retrospective analysis of 95 patients with myelofibrosis who were allografted between 2001 and 2014. The aims of the study were to assess whether the outcome of alternative donor grafts has improved with time and how this compares with the outcome of identical sibling grafts. Patients were studied in 2 time intervals: 2000 to 2010 (n = 58) and 2011 to 2014 (n = 37). The Dynamic International Prognostic Scoring System score was comparable in the 2 time periods, but differences in the most recent group included older age (58 versus 53 years, P =004), more family haploidentical donors (54% versus 5%, P ",

keywords = "Haploidentical donors, Myelofibrosis, Unrelated donors",

author = "Stefania Bregante and Alida Dominietto and Anna Ghiso and Raiola, {Anna Maria} and Francesca Gualandi and Riccardo Varaldo and {Di Grazia}, Carmela and Teresa Lamparelli and Silvia Luchetti and Simona Geroldi and Lucia Casarino and Sarah Pozzi and Elisabetta Tedone and {Van Lint}, {Maria Teresa} and Federica Galaverna and Giovanni Barosi and A. Bacigalupo",

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doi = "10.1016/j.bbmt.2015.09.028",

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AU - Bregante, Stefania

AU - Dominietto, Alida

AU - Ghiso, Anna

AU - Raiola, Anna Maria

AU - Gualandi, Francesca

AU - Varaldo, Riccardo

AU - Di Grazia, Carmela

AU - Lamparelli, Teresa

AU - Luchetti, Silvia

AU - Geroldi, Simona

AU - Casarino, Lucia

AU - Pozzi, Sarah

AU - Tedone, Elisabetta

AU - Van Lint, Maria Teresa

AU - Galaverna, Federica

AU - Barosi, Giovanni

AU - Bacigalupo, A.

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AB - This is a retrospective analysis of 95 patients with myelofibrosis who were allografted between 2001 and 2014. The aims of the study were to assess whether the outcome of alternative donor grafts has improved with time and how this compares with the outcome of identical sibling grafts. Patients were studied in 2 time intervals: 2000 to 2010 (n = 58) and 2011 to 2014 (n = 37). The Dynamic International Prognostic Scoring System score was comparable in the 2 time periods, but differences in the most recent group included older age (58 versus 53 years, P =004), more family haploidentical donors (54% versus 5%, P

KW - Haploidentical donors

KW - Myelofibrosis

KW - Unrelated donors

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Improved Outcome of Alternative Donor Transplantations in Patients with Myelofibrosis: From Unrelated to Haploidentical Family Donors

Abstract

Keywords

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