Improved rheumatoid digital vasculitis in a patient treated with TNFα agent blocking (infliximab)

Maurizio Benucci, Francesca Li Gobbi, Gianantonio Saviola, Mariangela Manfredi

Research output: Contribution to journalArticle


Rheumatoid vasculitis (RV) is an uncommon but potentially catastrophic complication of rheumatoid arthritis (RA). There are few current extensive studies and no consensus regarding the clinical, laboratory, histologic features and management or prognosis of RV. We report a case of RV in a 74-year old woman with a long (14 years) history of RA, who developed vasculitis of distal arteries with gangrene of digits of upper and lower extremities. After the failure of various immunosuppressive drugs (cyclophosphamide, methotrexate), the patient was treated with anti-TNFalpha infliximab. Digital gangrene healed within four months from the start of anti-TNFalpha treatment.

Original languageEnglish
Pages (from-to)1253-1255
Number of pages3
JournalRheumatology International
Issue number12
Publication statusPublished - Oct 2008



  • Rheumatoid vasculitis
  • TNFα blocking agents

ASJC Scopus subject areas

  • Rheumatology

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