Abstract
Improved health-related quality of life (HRQOL) and reduced activity limitations are prime objectives of migraine therapy, but no data on the effect of preventive treatments on these outcomes are available. We monitored changes in HRQOL using the Short Form 36 (SF-36) and headache-related activity limitations using the Migraine Disability Assessment Score (MIDAS) in 141 consecutive migraine without aura patients on prophylaxis. A total of 102 patients completed the 3-month study. Mean (SD) number of headache days/month dropped from 8.0 (3.7) to 5.0 (2.3) (P <0.001). Mean monthly consumption of acute drugs reduced from 7.4 (3.5) to 4.4 (3.1) (P <0.001). MIDAS total score reduced (improved) significantly. All SF-36 scale scores increased (improved), most significantly. This first study to assess prospectively the impact of prophylaxis on HRQOL and daily activities in a large series indicates that migraine prophylaxis has the potential to reduce the global burden of migraine on individuals and society.
| Original language | English |
|---|---|
| Pages (from-to) | 691-696 |
| Number of pages | 6 |
| Journal | Cephalalgia |
| Volume | 26 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jun 2006 |
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Keywords
- Activity limitations
- Health-related quality of life (HRQoL)
- Migraine
- Migraine disability assessment score (MIDAS)
- Prophylaxis
- Short form 36 (SF-36)
ASJC Scopus subject areas
- Clinical Neurology
Cite this
Improvement in quality of life and activity limitations in migraine patients after prophylaxis. A prospective longitudinal multicentre study. / D'Amico, D.; Solari, A.; Usai, S.; Santoro, P.; Bernardoni, P.; Frediani, F.; De Marco, R.; Massetto, N.; Bussone, G.
In: Cephalalgia, Vol. 26, No. 6, 06.2006, p. 691-696.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Improvement in quality of life and activity limitations in migraine patients after prophylaxis. A prospective longitudinal multicentre study
AU - D'Amico, D.
AU - Solari, A.
AU - Usai, S.
AU - Santoro, P.
AU - Bernardoni, P.
AU - Frediani, F.
AU - De Marco, R.
AU - Massetto, N.
AU - Bussone, G.
PY - 2006/6
Y1 - 2006/6
N2 - Improved health-related quality of life (HRQOL) and reduced activity limitations are prime objectives of migraine therapy, but no data on the effect of preventive treatments on these outcomes are available. We monitored changes in HRQOL using the Short Form 36 (SF-36) and headache-related activity limitations using the Migraine Disability Assessment Score (MIDAS) in 141 consecutive migraine without aura patients on prophylaxis. A total of 102 patients completed the 3-month study. Mean (SD) number of headache days/month dropped from 8.0 (3.7) to 5.0 (2.3) (P <0.001). Mean monthly consumption of acute drugs reduced from 7.4 (3.5) to 4.4 (3.1) (P <0.001). MIDAS total score reduced (improved) significantly. All SF-36 scale scores increased (improved), most significantly. This first study to assess prospectively the impact of prophylaxis on HRQOL and daily activities in a large series indicates that migraine prophylaxis has the potential to reduce the global burden of migraine on individuals and society.
AB - Improved health-related quality of life (HRQOL) and reduced activity limitations are prime objectives of migraine therapy, but no data on the effect of preventive treatments on these outcomes are available. We monitored changes in HRQOL using the Short Form 36 (SF-36) and headache-related activity limitations using the Migraine Disability Assessment Score (MIDAS) in 141 consecutive migraine without aura patients on prophylaxis. A total of 102 patients completed the 3-month study. Mean (SD) number of headache days/month dropped from 8.0 (3.7) to 5.0 (2.3) (P <0.001). Mean monthly consumption of acute drugs reduced from 7.4 (3.5) to 4.4 (3.1) (P <0.001). MIDAS total score reduced (improved) significantly. All SF-36 scale scores increased (improved), most significantly. This first study to assess prospectively the impact of prophylaxis on HRQOL and daily activities in a large series indicates that migraine prophylaxis has the potential to reduce the global burden of migraine on individuals and society.
KW - Activity limitations
KW - Health-related quality of life (HRQoL)
KW - Migraine
KW - Migraine disability assessment score (MIDAS)
KW - Prophylaxis
KW - Short form 36 (SF-36)
UR - http://www.scopus.com/inward/record.url?scp=33745187307&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33745187307&partnerID=8YFLogxK
U2 - 10.1111/j.1468-2982.2005.01094.x
DO - 10.1111/j.1468-2982.2005.01094.x
M3 - Article
C2 - 16686908
AN - SCOPUS:33745187307
VL - 26
SP - 691
EP - 696
JO - Cephalalgia
JF - Cephalalgia
SN - 0333-1024
IS - 6
ER -