Improvement of decreased natural killer cell activity in cervical cancer patients by active lipids (AL 721)

G. G. Garzetti, M. Cignitti, F. Marchegiani, M. Provinciali, A. M. Z aia, N. Fabris, C. Pieri, C. Romanini

Research output: Contribution to journalArticle

Abstract

In the present study we observed the absolute number of NK cells and the NK activity in 10 patients with cervical cancer. NK activity was determined before and after stimulation with Active Lipids. We reported a significant decrease of basal NK activity, but after AL stimulation NK activity was increased with statistical significance. Therefore our findings show that the reduction of NK activity in neoplastic patients is not an irreversible phenomenon since it can be restored by 'in vitro' AL administration. This is important for the adoptive immunotherapy by which we could give LAK cells to the patients.

Original languageEnglish
Pages (from-to)123-125
Number of pages3
JournalEuropean Journal of Gynaecological Oncology
Volume11
Issue number2
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Oncology

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    Garzetti, G. G., Cignitti, M., Marchegiani, F., Provinciali, M., Z aia, A. M., Fabris, N., Pieri, C., & Romanini, C. (1990). Improvement of decreased natural killer cell activity in cervical cancer patients by active lipids (AL 721). European Journal of Gynaecological Oncology, 11(2), 123-125.