Improvement of hand dexterity following motor cortex rTMS in multiple sclerosis patients with cerebellar impairment

Giacomo Koch, S. Rossi, C. Prosperetti, C. Codecà, F. Monteleone, L. Petrosini, G. Bernardi, D. Centonze

Research output: Contribution to journal › Article › peer-review

Abstract

We tested the effects of 5-Hz repetitive transcranial magnetic stimulation (rTMS) over the motor cortex in multiple sclerosis (MS) subjects with cerebellar symptoms. rTMS improved hand dexterity in cerebellar patients (n = 8) but not in healthy subjects (n = 7), as detected by a significant transient reduction of the time required to complete the nine-hole pegboard task. rTMS of the motor cortex may be a useful approach to treat cerebellar impairment in MS patients.

Original languageEnglish
Pages (from-to)995-998
Number of pages4
JournalMultiple Sclerosis Journal
Volume14
Issue number7
DOIs
Publication statusPublished - 2008

Keywords

  • Cerebellum
  • Motor functions
  • Multiple sclerosis
  • rTMS
  • Transcranial magnetic stimulation

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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