Improvement of hand dexterity following motor cortex rTMS in multiple sclerosis patients with cerebellar impairment

Giacomo Koch; S. Rossi; C. Prosperetti; C. Codecà; F. Monteleone; L. Petrosini; G. Bernardi; D. Centonze

doi:10.1177/1352458508088710

Improvement of hand dexterity following motor cortex rTMS in multiple sclerosis patients with cerebellar impairment

Giacomo Koch, S. Rossi, C. Prosperetti, C. Codecà, F. Monteleone, L. Petrosini, G. Bernardi, D. Centonze

Research output: Contribution to journal › Article › peer-review

Abstract

We tested the effects of 5-Hz repetitive transcranial magnetic stimulation (rTMS) over the motor cortex in multiple sclerosis (MS) subjects with cerebellar symptoms. rTMS improved hand dexterity in cerebellar patients (n = 8) but not in healthy subjects (n = 7), as detected by a significant transient reduction of the time required to complete the nine-hole pegboard task. rTMS of the motor cortex may be a useful approach to treat cerebellar impairment in MS patients.

Original language	English
Pages (from-to)	995-998
Number of pages	4
Journal	Multiple Sclerosis Journal
Volume	14
Issue number	7
DOIs	https://doi.org/10.1177/1352458508088710
Publication status	Published - 2008

Keywords

Cerebellum
Motor functions
Multiple sclerosis
rTMS
Transcranial magnetic stimulation

ASJC Scopus subject areas

Clinical Neurology
Neurology

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10.1177/1352458508088710

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abstract = "We tested the effects of 5-Hz repetitive transcranial magnetic stimulation (rTMS) over the motor cortex in multiple sclerosis (MS) subjects with cerebellar symptoms. rTMS improved hand dexterity in cerebellar patients (n = 8) but not in healthy subjects (n = 7), as detected by a significant transient reduction of the time required to complete the nine-hole pegboard task. rTMS of the motor cortex may be a useful approach to treat cerebellar impairment in MS patients.",

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AU - Koch, Giacomo

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AU - Codecà, C.

AU - Monteleone, F.

AU - Petrosini, L.

AU - Bernardi, G.

AU - Centonze, D.

PY - 2008

Y1 - 2008

N2 - We tested the effects of 5-Hz repetitive transcranial magnetic stimulation (rTMS) over the motor cortex in multiple sclerosis (MS) subjects with cerebellar symptoms. rTMS improved hand dexterity in cerebellar patients (n = 8) but not in healthy subjects (n = 7), as detected by a significant transient reduction of the time required to complete the nine-hole pegboard task. rTMS of the motor cortex may be a useful approach to treat cerebellar impairment in MS patients.

AB - We tested the effects of 5-Hz repetitive transcranial magnetic stimulation (rTMS) over the motor cortex in multiple sclerosis (MS) subjects with cerebellar symptoms. rTMS improved hand dexterity in cerebellar patients (n = 8) but not in healthy subjects (n = 7), as detected by a significant transient reduction of the time required to complete the nine-hole pegboard task. rTMS of the motor cortex may be a useful approach to treat cerebellar impairment in MS patients.

KW - Cerebellum

KW - Motor functions

KW - Multiple sclerosis

KW - rTMS

KW - Transcranial magnetic stimulation

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Improvement of hand dexterity following motor cortex rTMS in multiple sclerosis patients with cerebellar impairment

Abstract

Keywords

ASJC Scopus subject areas

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