Varenicline is a partial agonist at the α4β2 nicotinic acetylcholine receptor effective as smoking cessation pharmacotherapy. We present a familial case of severe restless legs syndrome (RLS) resistant to polytherapy who showed a consistent and effective amelioration of RLS symptoms after introduction of varenicline as antismoking drug.
- Nicotinic acetylcholine receptor agonist
- Restless legs syndrome
ASJC Scopus subject areas
- Clinical Neurology
- Pulmonary and Respiratory Medicine