Improving cardiovascular risk stratification in essential hypertensive patients by indexing left ventricular mass to height2.7

Cesare Cuspidi, Valentina Giudici, Francesca Negri, Stefano Meani, Carla Sala, Alberto Zanchetti, Giuseppe Mancia

Research output: Contribution to journalArticle


AIM: Clinical abnormalities associated with left ventricular hypertrophy (LVH) only defined by left ventricular mass (LVM) indexed to height are still undefined. We investigated the prevalence, clinical correlates and extracardiac organ damage of such a cardiac phenotype in essential hypertensive patients. METHODS: Subclinical organ damage was searched in 3719 untreated and treated hypertensive patients. LVH was defined by two sets of sex-specific criteria, namely, LVM indexed to height (left ventricular mass index >49/45 g/m in men and women, respectively) and LVM indexed to body surface area (BSA; left ventricular mass index >125/110 g/m in men and women, respectively). Patients were categorized into three groups, according to the absence of LVH by both criteria (n ≤ 1912, group I), presence of LVH by the height criterion only (n ≤ 784, group II) and presence of LVH by both criteria (n ≤ 997, group III). A fourth group (n ≤ 26,

Original languageEnglish
Pages (from-to)2465-2471
Number of pages7
JournalJournal of Hypertension
Issue number12
Publication statusPublished - Dec 2009



  • Hypertension
  • Left ventricular hypertrophy
  • Left ventricular mass indexation

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

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