Improving Provision of Care for Long-term Survivors of Lymphoma

Sabino Ciavarella, Carla Minoia, Angela Maria Quinto, Stefano Oliva, Santa Carbonara, Claudia Cormio, Maria Christina Cox, Elena Bravo, Filippo Santoro, Mariarosaria Napolitano, Michele Spina, Giacomo Loseto, Attilio Guarini

Research output: Contribution to journalReview articlepeer-review


The progressive improvement of lymphoma therapies has led to a significant prolongation of patient survival and life expectancy. However, lymphoma survivors are at high risk of experiencing a range of early and late adverse effects associated with the extent of treatment exposure. Among these, second malignancies and cardiopulmonary diseases can be fatal, and neurocognitive dysfunction, endocrinopathy, muscle atrophy, and persistent fatigue can affect patients' quality of life for decades after treatment. Early recognition and reduction of risk factors and proper monitoring and treatment of these complications require well-defined follow-up criteria, close coordination among specialists of different disciplines, and a tailored model of survivorship care. We have summarized the major aspects of therapy-related effects in lymphoma patients, reviewed the current recommendations for follow-up protocols, and described a new hospital-based model of survivorship care provision from a recent multicenter Italian experience.

Original languageEnglish
Pages (from-to)e1-e9
JournalClinical Lymphoma, Myeloma and Leukemia
Issue number12
Publication statusPublished - Dec 1 2017


  • Long-term complications
  • Long-term follow-up
  • Lymphoma survivors
  • Survivorship recommendations
  • Therapy-related toxicity

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research


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