In situ mapping of the gene coding for a leucine zipper DNA binding protein (CDR62) to 16p12-16p13.1

T. Gress; A. Baldini; M. Rocchi; H. Furneaux; J. B. Posner; M. Siniscalco

doi:10.1016/0888-7543(92)90063-X

In situ mapping of the gene coding for a leucine zipper DNA binding protein (CDR62) to 16p12-16p13.1

T. Gress, A. Baldini, M. Rocchi, H. Furneaux, J. B. Posner, M. Siniscalco

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Abstract

A cDNA clone encoding the major antigen (CDR62) associated with the antibody-induced paraneoplastic cerebellar degeneration has been used to identify the chromosomal location of the corresponding structural gene(s) by screening for its retention in a panel of rodent-human somatic cell hybrids. Having established the synteny of the gene with the autosome 16, we proceeded to its precise subregional mapping by in situ fluorescence hybridization with a recombinant lambda phage containing the genomic region homologous to the cDNA gene. The latter studies pin-pointed the chromosomal localization of the structural CDR62 gene within the interval 16p12-16p13.1.

Original language	English
Pages (from-to)	1340-1342
Number of pages	3
Journal	Genomics
Volume	13
Issue number	4
DOIs	https://doi.org/10.1016/0888-7543(92)90063-X
Publication status	Published - 1992

ASJC Scopus subject areas

Genetics

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title = "In situ mapping of the gene coding for a leucine zipper DNA binding protein (CDR62) to 16p12-16p13.1",

abstract = "A cDNA clone encoding the major antigen (CDR62) associated with the antibody-induced paraneoplastic cerebellar degeneration has been used to identify the chromosomal location of the corresponding structural gene(s) by screening for its retention in a panel of rodent-human somatic cell hybrids. Having established the synteny of the gene with the autosome 16, we proceeded to its precise subregional mapping by in situ fluorescence hybridization with a recombinant lambda phage containing the genomic region homologous to the cDNA gene. The latter studies pin-pointed the chromosomal localization of the structural CDR62 gene within the interval 16p12-16p13.1.",

author = "T. Gress and A. Baldini and M. Rocchi and H. Furneaux and Posner, {J. B.} and M. Siniscalco",

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T1 - In situ mapping of the gene coding for a leucine zipper DNA binding protein (CDR62) to 16p12-16p13.1

AU - Gress, T.

AU - Baldini, A.

AU - Rocchi, M.

AU - Furneaux, H.

AU - Posner, J. B.

AU - Siniscalco, M.

PY - 1992

Y1 - 1992

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