In vitro activity of a new antibacterial drug, trospectomycin sulphate (U-63,366F), against Bacteroides strains isolated from the vagina

Gian Piero Testore, Lucilla Terranova, Agata Salanitro, Pasquale Sordillo, Andrea Foli, Francesco Giacomello, Massimo Andreoni

Research output: Contribution to journalArticlepeer-review

Abstract

The antibacterial activity of trospectomycin, clindamycin, metronidazole, imipenem, cefoxitin, and piperacillin was tested against 72 Bacteroides spp. strains isolated from the vagina of women with vaginitis by determining the minimal inhibitory concentration using the agar dilution method. Trospectomycin shows a good activity which is comparable to that of imipenem and metronidazole. Its expanded spectrum of activity makes trospectomycin suitable for the use in single-drug therapy of pelvic infections in women.

Original languageEnglish
Pages (from-to)124-127
Number of pages4
JournalChemotherapy
Volume39
Issue number2
DOIs
Publication statusPublished - 1993

Keywords

  • Anaerobic susceptibility
  • Gynaecological infections
  • Pelvic inflammatory disease
  • Trospectomycin

ASJC Scopus subject areas

  • Infectious Diseases
  • Oncology
  • Pharmacology (medical)
  • Drug Discovery
  • Pharmacology

Fingerprint Dive into the research topics of 'In vitro activity of a new antibacterial drug, trospectomycin sulphate (U-63,366F), against Bacteroides strains isolated from the vagina'. Together they form a unique fingerprint.

Cite this