In vitro activity of ABT773, a new ketolide derivative exhibiting innovative microbiological properties against well-characterised antibiotic resistant pathogens in Italy

Micaela Bozzolasco; Eugenio A. Debbia; Simona Roveta; Anna Maria Schito; Anna Marchese

doi:10.1016/j.ijantimicag.2003.05.012

In vitro activity of ABT773, a new ketolide derivative exhibiting innovative microbiological properties against well-characterised antibiotic resistant pathogens in Italy

Micaela Bozzolasco, Eugenio A. Debbia, Simona Roveta, Anna Maria Schito, Anna Marchese

A.O.U. San Martino - IST, Istituto Nazionale Ricerca sul Cancro (GENOVA)

Research output: Contribution to journal › Article › peer-review

Abstract

The in vitro activity of ABT773, a new ketolide, was assessed against a collection (518) of well-characterised Gram-positive and Gram-negative pathogens and compared with that of other appropriate drugs. ABT773 was active (MIC-90=0.03mg/l) against the staphylococci tested which included macrolide-resistant but clindamycin susceptible organisms. Streptococcus pneumoniae, S. pyogenes and S. agalactiae were also inhibited (MIC-90 range:

Original language	English
Pages (from-to)	11-16
Number of pages	6
Journal	International Journal of Antimicrobial Agents
Volume	23
Issue number	1
DOIs	https://doi.org/10.1016/j.ijantimicag.2003.05.012
Publication status	Published - Jan 2004

Keywords

ABT773
Erythromycin resistance
Ketolides

ASJC Scopus subject areas

Applied Microbiology and Biotechnology
Microbiology
Parasitology
Virology
Immunology and Allergy
Infectious Diseases

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10.1016/j.ijantimicag.2003.05.012

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In vitro activity of ABT773, a new ketolide derivative exhibiting innovative microbiological properties against well-characterised antibiotic resistant pathogens in Italy. / Bozzolasco, Micaela; Debbia, Eugenio A.; Roveta, Simona; Schito, Anna Maria; Marchese, Anna.

In: International Journal of Antimicrobial Agents, Vol. 23, No. 1, 01.2004, p. 11-16.

Research output: Contribution to journal › Article › peer-review

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