In vitro and in vivo evaluation of human satellite muscle stem cells

Chiara Dell Agnola, Cristina Rabascio, Patrizial Mancuso, Manuela Capillo, Alberto Gobbi, Silvia Monestiroli, Nicoletta Tradati, Luca Calabrese, Massimo Corsaro, Sara Volorio, Giovanni Martinelli, Francesco Bertolini

Research output: Contribution to journalArticlepeer-review


There is rising evidence that the potential of stem cells is not restricted by theiri source. Brain stem cells can reconstitute hematopoiesis, and bone marrow (BM) cells can generate muscle, brain and liver tissue. Along this line, it has been reported that mouse satellite muscle stem cells can reconstitute hematopoiesis in lethally irradiated recipients. We studied human satellite stem cells (SSC) generated from muscle surgically removed from head and neck cancer patients. Muscle samples were minced, digested and cultured in F12-10% FBS according to the literature. In SSC cultures derived from

Original languageEnglish
Issue number11 PART I
Publication statusPublished - 2000

ASJC Scopus subject areas

  • Hematology


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