In vitro approaches

Muriel Cario-André, Maria Lucia Dell'Anna

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Core Messages: The complexity of cell culture models varies from monolayers for adherent cells or suspensions for nonadherent cells, to cocultures or to epidermal reconstructs (3D model). Cocultures and epidermal reconstructs allow the study of paracrine or contact cell-cell effects. The tests on nonepidermal nonadherent cells, such as peripheral blood mononuclear cells (PBMC) expand the view, going beyond mel-anogenesis-associated metabolisms. The in vitro studies on hair follicle melanocytes help understand the maturation and differentiation of melanocytes and to unveil the defective steps of growth and migration in melanocyte precursors during the repigmentation. New analytic techniques are emerging which can be applied for investigating vitiligo.

Original languageEnglish
Title of host publicationVitiligo
PublisherSpringer Berlin Heidelberg
Pages219-230
Number of pages12
ISBN (Print)9783540693604
DOIs
Publication statusPublished - 2010

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'In vitro approaches'. Together they form a unique fingerprint.

  • Cite this

    Cario-André, M., & Dell'Anna, M. L. (2010). In vitro approaches. In Vitiligo (pp. 219-230). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-540-69361-1_26