'In vitro' megakaryocytopoiesis in patients with HIV-related thrombocytopenic purpura

Research output: Contribution to journalArticle

Abstract

In order to investigate the mechanism(s) of thrombocytopenia in HIV-infected patients, a clonal culture system was used that allows the growth of bone marrow-derived megakaryocytic progenitor cells (CFU-Mk). Six patients with HIV-related thrombocytopenia were evaluated for the in vitro growth of megakaryocytic progenitor cells. In all patients a significant reduction in the growth (mean ± SEM) of CFU-Mk (2.3 ± 1, P

Original languageEnglish
Pages (from-to)25-30
Number of pages6
JournalHaematologica
Volume73
Issue number1
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Hematology

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