Acanthamoeba keratitis is a severe ocular infection. An increased incidence of the infection was recorded among contact lens wearers with poor hygiene. The severity of the disease was also due in the past to the lack of efficacious topic and systemic drugs. We therefore evaluated the in vitro effectiveness of providone iodine (Betadine®), PVD-I), a solution of polyvinilpyrrolidone and 10% iodine, compared to chlorhexidine (CLX), a cationic antiseptic, on vegetative and cystic stages of Acanthamoeba spp. isolates from patients with amoebic keratitis. The results showed that PVD-I has a better antiamebic activity both on trophic and cystic stages of the isolates than CLX.
|Translated title of the contribution||In vitro susceptibility to betadine® of Acanthamoeba isolates from patients with keratitis|
|Number of pages||8|
|Journal||Acta Medica Romana|
|Publication status||Published - 1998|
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