Human immunodeficiency virus type 1 (HIV-1)-infected patients (n = 335) in the US Air Force HIV Natural History Program were followed for 3 years (mean) after skin testing, immunophenotyping of CD4+ cell subsets, and measurement of in vitro interleukin-2 production after stimulation by phytohemagglutinin, alloantigens, tetanus toxoid, and influenza A virus. The T cell functional assay predicted survival time (P + T cells (P =.001), the percentage of CD4+CD29+ cells (P =.06), and the number of reactive skin tests (P + cell count.
ASJC Scopus subject areas
- Infectious Diseases
- Immunology and Allergy
- Public Health, Environmental and Occupational Health