In Vivo and Ex Vivo Confocal Microscopy for Dermatologic and Mohs Surgeons

Caterina Longo; Moira Ragazzi; Milind Rajadhyaksha; Kishwer Nehal; Antoni Bennassar; Giovanni Pellacani; Josep Malvehy Guilera

doi:10.1016/j.det.2016.05.012

In Vivo and Ex Vivo Confocal Microscopy for Dermatologic and Mohs Surgeons

Caterina Longo, Moira Ragazzi, Milind Rajadhyaksha, Kishwer Nehal, Antoni Bennassar, Giovanni Pellacani, Josep Malvehy Guilera

Arcispedale Santa Maria Nuova

Research output: Contribution to journal › Review article

Abstract

Confocal microscopy is a modern imaging device that has been extensively applied in skin oncology. More specifically, for tumor margin assessment, it has been used in two modalities: reflectance mode (in vivo on skin patient) and fluorescence mode (on freshly excised specimen). Although in vivo reflectance confocal microscopy is an add-on tool for lentigo maligna mapping, fluorescence confocal microscopy is far superior for basal cell carcinoma and squamous cell carcinoma margin assessment in the Mohs setting. This article provides a comprehensive overview of the use of confocal microscopy for skin cancer margin evaluation.

Original language	English
Pages (from-to)	497-504
Number of pages	8
Journal	Dermatologic Clinics
Volume	34
Issue number	4
DOIs	https://doi.org/10.1016/j.det.2016.05.012
Publication status	Published - Oct 1 2016

Keywords

Confocal microscopy
Ex vivo
In vivo
Mohs surgery

ASJC Scopus subject areas

Dermatology

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10.1016/j.det.2016.05.012

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Cite this

Longo, C., Ragazzi, M., Rajadhyaksha, M., Nehal, K., Bennassar, A., Pellacani, G., & Malvehy Guilera, J. (2016). In Vivo and Ex Vivo Confocal Microscopy for Dermatologic and Mohs Surgeons. Dermatologic Clinics, 34(4), 497-504. https://doi.org/10.1016/j.det.2016.05.012

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abstract = "Confocal microscopy is a modern imaging device that has been extensively applied in skin oncology. More specifically, for tumor margin assessment, it has been used in two modalities: reflectance mode (in vivo on skin patient) and fluorescence mode (on freshly excised specimen). Although in vivo reflectance confocal microscopy is an add-on tool for lentigo maligna mapping, fluorescence confocal microscopy is far superior for basal cell carcinoma and squamous cell carcinoma margin assessment in the Mohs setting. This article provides a comprehensive overview of the use of confocal microscopy for skin cancer margin evaluation.",

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AU - Longo, Caterina

AU - Ragazzi, Moira

AU - Rajadhyaksha, Milind

AU - Nehal, Kishwer

AU - Bennassar, Antoni

AU - Pellacani, Giovanni

AU - Malvehy Guilera, Josep

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KW - Confocal microscopy

KW - Ex vivo

KW - In vivo

KW - Mohs surgery

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