TY - JOUR
T1 - In Vivo and Ex Vivo Confocal Microscopy for Dermatologic and Mohs Surgeons
AU - Longo, Caterina
AU - Ragazzi, Moira
AU - Rajadhyaksha, Milind
AU - Nehal, Kishwer
AU - Bennassar, Antoni
AU - Pellacani, Giovanni
AU - Malvehy Guilera, Josep
PY - 2016/10/1
Y1 - 2016/10/1
N2 - Confocal microscopy is a modern imaging device that has been extensively applied in skin oncology. More specifically, for tumor margin assessment, it has been used in two modalities: reflectance mode (in vivo on skin patient) and fluorescence mode (on freshly excised specimen). Although in vivo reflectance confocal microscopy is an add-on tool for lentigo maligna mapping, fluorescence confocal microscopy is far superior for basal cell carcinoma and squamous cell carcinoma margin assessment in the Mohs setting. This article provides a comprehensive overview of the use of confocal microscopy for skin cancer margin evaluation.
AB - Confocal microscopy is a modern imaging device that has been extensively applied in skin oncology. More specifically, for tumor margin assessment, it has been used in two modalities: reflectance mode (in vivo on skin patient) and fluorescence mode (on freshly excised specimen). Although in vivo reflectance confocal microscopy is an add-on tool for lentigo maligna mapping, fluorescence confocal microscopy is far superior for basal cell carcinoma and squamous cell carcinoma margin assessment in the Mohs setting. This article provides a comprehensive overview of the use of confocal microscopy for skin cancer margin evaluation.
KW - Confocal microscopy
KW - Ex vivo
KW - In vivo
KW - Mohs surgery
UR - http://www.scopus.com/inward/record.url?scp=84992401756&partnerID=8YFLogxK
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U2 - 10.1016/j.det.2016.05.012
DO - 10.1016/j.det.2016.05.012
M3 - Review article
AN - SCOPUS:84992401756
VL - 34
SP - 497
EP - 504
JO - Dermatologic Clinics
JF - Dermatologic Clinics
SN - 0733-8635
IS - 4
ER -