In Vivo and Ex Vivo Confocal Microscopy for Dermatologic and Mohs Surgeons

Caterina Longo, Moira Ragazzi, Milind Rajadhyaksha, Kishwer Nehal, Antoni Bennassar, Giovanni Pellacani, Josep Malvehy Guilera

Research output: Contribution to journalReview articlepeer-review

Abstract

Confocal microscopy is a modern imaging device that has been extensively applied in skin oncology. More specifically, for tumor margin assessment, it has been used in two modalities: reflectance mode (in vivo on skin patient) and fluorescence mode (on freshly excised specimen). Although in vivo reflectance confocal microscopy is an add-on tool for lentigo maligna mapping, fluorescence confocal microscopy is far superior for basal cell carcinoma and squamous cell carcinoma margin assessment in the Mohs setting. This article provides a comprehensive overview of the use of confocal microscopy for skin cancer margin evaluation.

Original languageEnglish
Pages (from-to)497-504
Number of pages8
JournalDermatologic Clinics
Volume34
Issue number4
DOIs
Publication statusPublished - Oct 1 2016

Keywords

  • Confocal microscopy
  • Ex vivo
  • In vivo
  • Mohs surgery

ASJC Scopus subject areas

  • Dermatology

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