In vivo and ex vivo magnetic resonance spectroscopy in the characterization of hemangioblastoma cyst fluid

Girolamo Crisi; Silvano Filice; Thelma A. Pertinhez; Elisa Ventura; Franco Servadei

doi:10.1097/RCT.0b013e3182a9103a

In vivo and ex vivo magnetic resonance spectroscopy in the characterization of hemangioblastoma cyst fluid

Girolamo Crisi, Silvano Filice, Thelma A. Pertinhez, Elisa Ventura, Franco Servadei

Arcispedale Santa Maria Nuova

Research output: Contribution to journal › Article › peer-review

Abstract

ABSTRACT: Peritumoral cyst formation is commonly associated with hemangioblastomas of the central nervous system. Results of a proteomic profiling of hemangioblastoma cyst fluid suggested that cyst formation, whether intratumoral or peritumoral, is a consequence of vascular leakage because protein profiles of cyst fluid and blood serum were similar. To the best of our knowledge, this is the first report of in vivo and ex vivo magnetic resonance spectroscopy analyses of hemangioblastoma cyst fluid that investigates on the mechanism leading to peritumoral cyst formation.

Original language	English
Pages (from-to)	29-32
Number of pages	4
Journal	Journal of Computer Assisted Tomography
Volume	38
Issue number	1
DOIs	https://doi.org/10.1097/RCT.0b013e3182a9103a
Publication status	Published - Jan 2014

Keywords

Cyst
Hemangioblastoma
MR spectroscopy

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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abstract = "ABSTRACT: Peritumoral cyst formation is commonly associated with hemangioblastomas of the central nervous system. Results of a proteomic profiling of hemangioblastoma cyst fluid suggested that cyst formation, whether intratumoral or peritumoral, is a consequence of vascular leakage because protein profiles of cyst fluid and blood serum were similar. To the best of our knowledge, this is the first report of in vivo and ex vivo magnetic resonance spectroscopy analyses of hemangioblastoma cyst fluid that investigates on the mechanism leading to peritumoral cyst formation.",

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AU - Ventura, Elisa

AU - Servadei, Franco

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AB - ABSTRACT: Peritumoral cyst formation is commonly associated with hemangioblastomas of the central nervous system. Results of a proteomic profiling of hemangioblastoma cyst fluid suggested that cyst formation, whether intratumoral or peritumoral, is a consequence of vascular leakage because protein profiles of cyst fluid and blood serum were similar. To the best of our knowledge, this is the first report of in vivo and ex vivo magnetic resonance spectroscopy analyses of hemangioblastoma cyst fluid that investigates on the mechanism leading to peritumoral cyst formation.

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