In vivo cholinergic circuit evaluation in frontotemporal and Alzheimer dementias

V. Di Lazzaro, F. Pilato, M. Dileone, E. Saturno, A. Oliviero, C. Marra, A. Daniele, F. Ranieri, G. Gainotti, P. A. Tonali

Research output: Contribution to journalArticle

Abstract

The test of short latency afferent inhibition (SAI) of the motor cortex is helpful in demonstrating dysfunction of central cholinergic circuits in Alzheimer disease (AD). The authors evaluated SAI in 20 patients with frontotemporal dementia (FTD) and compared data with those from 20 patients with AD and 20 controls. SAI was normal in FTD, whereas it was reduced in AD. SAI may represent an additional tool to discriminate FTD from AD.

Original languageEnglish
Pages (from-to)1111-1113
Number of pages3
JournalNeurology
Volume66
Issue number7
DOIs
Publication statusPublished - Apr 2006

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ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Di Lazzaro, V., Pilato, F., Dileone, M., Saturno, E., Oliviero, A., Marra, C., Daniele, A., Ranieri, F., Gainotti, G., & Tonali, P. A. (2006). In vivo cholinergic circuit evaluation in frontotemporal and Alzheimer dementias. Neurology, 66(7), 1111-1113. https://doi.org/10.1212/01.wnl.0000204183.26231.23