Abstract
Purpose: Our aim was to estimate the in vivo reproducibility of bone mineral density (BMD) at dual-energy X-ray absorptiometry (DXA) and to compare fast array, array, and high-definition scan modes. Materials and methods: A total of 378 patients (38 males and 340 females; mean age 63 ± 9 years) underwent DXA using a QDR-Discovery A densitometer (Hologic). Considering the three scan modes on lumbar spine and right femur, six independent groups of 30 patients were examined twice (for a total of 180 patients). Least significant change (LSC) and smallest detectable difference (SDD) were calculated. The remaining 198 patients underwent three scans of the lumbar spine (n = 92) or of the right femur (n = 106), one for each scan mode. The student t test and Bland-Altman analysis used were. Scan times were recorded and radiation dose was estimated using the ICRP60 method. Results: Intra-scan mode reproducibility was 98-99 %, corresponding to an LSC of 1.49-2.08 %. The SDD was 0.018-0.023 g/cm2 (lumbar spine) and 0.017-0.019 g/cm2 (right femur). All comparisons among scan modes were statistically significant (p <0.001) but lower than SDDs, i.e. not clinically relevant. Considering lumbar spine and the right femur, scan times were 50 and 38 s for fast array, 98 and 74 s for array, and 195 and 148 s for high definition, respectively; radiation doses were 6.7 and 4.7 μSv for fast array, and 13.3 and 9.3 μSv for both array and high definition, respectively. Conclusion: Since all BMD differences were lower than the SSDs, the three scan modes can be considered interchangeable. As a consequence, although the absolute reduction in time and radiation dose is relatively low, when BMD measurement is the aim of DXA, fast array can be generally preferred.
| Original language | English |
|---|---|
| Pages (from-to) | 257-260 |
| Number of pages | 4 |
| Journal | Radiologia Medica |
| Volume | 119 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2014 |
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Keywords
- Bone mineral density
- Dual-energy X-ray absorptiometry
- Reproducibility
- Scan modes
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Medicine(all)
Cite this
In vivo differences among scan modes in bone mineral density measurement at dual-energy X-ray absorptiometry. / Bandirali, Michele; Sconfienza, Luca M.; Aliprandi, Alberto; Di Leo, Giovanni; Marchelli, Daniele; Ulivieri, Fabio M.; Sardanelli, Francesco.
In: Radiologia Medica, Vol. 119, No. 4, 2014, p. 257-260.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - In vivo differences among scan modes in bone mineral density measurement at dual-energy X-ray absorptiometry
AU - Bandirali, Michele
AU - Sconfienza, Luca M.
AU - Aliprandi, Alberto
AU - Di Leo, Giovanni
AU - Marchelli, Daniele
AU - Ulivieri, Fabio M.
AU - Sardanelli, Francesco
PY - 2014
Y1 - 2014
N2 - Purpose: Our aim was to estimate the in vivo reproducibility of bone mineral density (BMD) at dual-energy X-ray absorptiometry (DXA) and to compare fast array, array, and high-definition scan modes. Materials and methods: A total of 378 patients (38 males and 340 females; mean age 63 ± 9 years) underwent DXA using a QDR-Discovery A densitometer (Hologic). Considering the three scan modes on lumbar spine and right femur, six independent groups of 30 patients were examined twice (for a total of 180 patients). Least significant change (LSC) and smallest detectable difference (SDD) were calculated. The remaining 198 patients underwent three scans of the lumbar spine (n = 92) or of the right femur (n = 106), one for each scan mode. The student t test and Bland-Altman analysis used were. Scan times were recorded and radiation dose was estimated using the ICRP60 method. Results: Intra-scan mode reproducibility was 98-99 %, corresponding to an LSC of 1.49-2.08 %. The SDD was 0.018-0.023 g/cm2 (lumbar spine) and 0.017-0.019 g/cm2 (right femur). All comparisons among scan modes were statistically significant (p <0.001) but lower than SDDs, i.e. not clinically relevant. Considering lumbar spine and the right femur, scan times were 50 and 38 s for fast array, 98 and 74 s for array, and 195 and 148 s for high definition, respectively; radiation doses were 6.7 and 4.7 μSv for fast array, and 13.3 and 9.3 μSv for both array and high definition, respectively. Conclusion: Since all BMD differences were lower than the SSDs, the three scan modes can be considered interchangeable. As a consequence, although the absolute reduction in time and radiation dose is relatively low, when BMD measurement is the aim of DXA, fast array can be generally preferred.
AB - Purpose: Our aim was to estimate the in vivo reproducibility of bone mineral density (BMD) at dual-energy X-ray absorptiometry (DXA) and to compare fast array, array, and high-definition scan modes. Materials and methods: A total of 378 patients (38 males and 340 females; mean age 63 ± 9 years) underwent DXA using a QDR-Discovery A densitometer (Hologic). Considering the three scan modes on lumbar spine and right femur, six independent groups of 30 patients were examined twice (for a total of 180 patients). Least significant change (LSC) and smallest detectable difference (SDD) were calculated. The remaining 198 patients underwent three scans of the lumbar spine (n = 92) or of the right femur (n = 106), one for each scan mode. The student t test and Bland-Altman analysis used were. Scan times were recorded and radiation dose was estimated using the ICRP60 method. Results: Intra-scan mode reproducibility was 98-99 %, corresponding to an LSC of 1.49-2.08 %. The SDD was 0.018-0.023 g/cm2 (lumbar spine) and 0.017-0.019 g/cm2 (right femur). All comparisons among scan modes were statistically significant (p <0.001) but lower than SDDs, i.e. not clinically relevant. Considering lumbar spine and the right femur, scan times were 50 and 38 s for fast array, 98 and 74 s for array, and 195 and 148 s for high definition, respectively; radiation doses were 6.7 and 4.7 μSv for fast array, and 13.3 and 9.3 μSv for both array and high definition, respectively. Conclusion: Since all BMD differences were lower than the SSDs, the three scan modes can be considered interchangeable. As a consequence, although the absolute reduction in time and radiation dose is relatively low, when BMD measurement is the aim of DXA, fast array can be generally preferred.
KW - Bone mineral density
KW - Dual-energy X-ray absorptiometry
KW - Reproducibility
KW - Scan modes
UR - http://www.scopus.com/inward/record.url?scp=84898027700&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84898027700&partnerID=8YFLogxK
U2 - 10.1007/s11547-013-0342-3
DO - 10.1007/s11547-013-0342-3
M3 - Article
C2 - 24297585
AN - SCOPUS:84898027700
VL - 119
SP - 257
EP - 260
JO - Radiologia Medica
JF - Radiologia Medica
SN - 0033-8362
IS - 4
ER -